Evidence map›Paper›PMID 40829824›Full record

ArticleBMJ open2025

Application of machine learning in early childhood development research: a scoping review.

Faith Neema Benson, Daisy Chelangat, Willie Brink, Patrick N Mwangala, Akbar K Waljee, Cheryl A Moyer, Amina Abubakar

Abstract readScoping Review
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Artificial Intelligence and the future of clinical trials.Contemporary clinical trials communications · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Faith Neema BensonInstitute for Human Development, The Aga Khan University, Nairobi, Kenya faith.neema@aku.edu.ORCID http://orcid.org/0000-0002-4773-9684
Daisy ChelangatInstitute for Human Development, The Aga Khan University, Nairobi, Kenya.
Willie BrinkDepartment of Mathematical Sciences, Stellenbosch University, Stellenbosch, South Africa.
Patrick N MwangalaInstitute for Human Development, The Aga Khan University, Nairobi, Kenya.
Akbar K WaljeeDepartment of Learning Health Sciences, University of Michigan, Ann Arbor, Michigan, USA.
Cheryl A MoyerDepartment of Learning Health Sciences, University of Michigan, Ann Arbor, Michigan, USA.
Amina AbubakarInstitute for Human Development, The Aga Khan University, Nairobi, Kenya.ORCID http://orcid.org/0000-0002-3686-7904

Funding

UZIMA-DS: UtiliZing health Information for Meaningful Impact in East Africa through Data ScienceU54TW012089 · FIC · AGA KHAN UNIVERSITY (KENYA) · PI Amina Abubakar Ali, Akbar K Waljee · 2021 to 2026
$7.7M
FIC NIH HHS U54 TW012089
6 · The paper itself

Abstract

backgroundEarly childhood development (ECD) lays the foundation for lifelong health, academic success and social well-being, yet over 250 million children in low- and middle-income countries are at risk of not reaching their developmental potential. Traditional measures fail to fully capture the risks associated with a child's development outcomes. Artificial intelligence techniques, particularly machine learning (ML), offer an innovative approach by analysing complex datasets to detect subtle developmental patterns.

objectiveTo map the existing literature on the use of ML in ECD research, including its geographical distribution, to identify research gaps and inform future directions. The review focuses on applied ML techniques, data types, feature sets, outcomes, data splitting and validation strategies, model performance, model explainability, key themes, clinical relevance and reported limitations.

designScoping review using the Arksey and O'Malley framework with enhancements by Levac ELIGIBILITY CRITERIA: Included studies applied ML or its variants (eg, deep learning (DL), natural language processing) to developmental outcomes in children aged 0-8 years. Studies were in English and addressed cognitive, language, motor or social-emotional development. Excluded were studies focusing on robotics; neurodevelopmental disorders such as autism spectrum disorder, attention-deficit/hyperactivity disorder and communication disorders; disease or medical conditions; and review articles. DATA EXTRACTION AND CHARTING: Three reviewers independently extracted data using a structured MS Excel template, covering study ML techniques, data types, feature sets, outcomes, outcome measures, data splitting and validation strategies, model performance, model explainability, key themes, clinical relevance and limitations. A narrative synthesis was conducted, supported by descriptive statistics and visualisations.

resultsOf the 759 articles retrieved, 27 met the inclusion criteria. Most studies (78%) originated from high-income countries, with none from sub-Saharan Africa. Supervised ML classifiers (40.7%) and DL techniques (22.2%) were the most used approaches. Cognitive development was the most frequently targeted outcome (33.3%), often measured using the Bayley Scales of Infant and Toddler Development-III (33.3%). Data types varied, with image, video and sensor-based data being most prevalent. Key predictive features were grouped into six categories: brain features; anthropometric and clinical/biological markers; socio-demographic and environmental factors; medical history and nutritional indicators; linguistic and expressive features; and motor indicators. Most studies (74.1%) focused solely on prediction, with the majority conducting predictions at age 2 years and above. Only 41% of studies employed explainability methods, and validation strategies varied widely. Few studies (7.4%) conducted external validation, and only one had progressed to a clinical trial. Common limitations included small sample sizes, lack of external validation and imbalanced datasets.

conclusionThere is growing interest in using ML for ECD research, but current research lacks geographical diversity, external validation, explainability and practical implementation. Future work should focus on developing inclusive, interpretable and externally validated models that are integrated into real-world implementation.

Indexed as

Child DevelopmentMachine LearningChildChild, PreschoolHumansInfantChildCognitionMachine Learning

Identifiers

PMID40829824
PMCPMC12366570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.