Evidence map›Paper›PMID 40829816›Full record

ArticleBMJ open2025

Consensus on the definition, components, timeframe and grading of composite outcome of postoperative pulmonary complication-protocol for an international mixed-method consensus study (PrECiSIOn).

Prashant Nasa, Timur Yurttas, Denise Battaglini, Stijn Blot, Ana Fernandez-Bustamante, Marcelo Gama de Abreu, David M van Meenen, Sheila Nainan Myatra, Ary Serpa Neto, Raymond Oppong and 6 more

2 registry-linked trialsAbstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06916598 enrolling by invitationnot on this map

Consensus Statements on Definition, Components and Grading of Postoperative Pulmonary Complications- an International Delphi Study

TypeobservationalSponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Ran2025 to 2026Enrolled40ConditionsPostoperative Pulmonary ComplicationsArmsDelphi study, Structured Interview
NCT07638540 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Standardising Terminology, Classification, Diagnostic Recognition and Reporting of Patient-Ventilator Interactions: Protocol for an International Delphi Consensus Study (INTERACT)

TypeobservationalSponsorAl Adan Hospital KuwaitRan2026 to 2027Enrolled50ConditionsPatient-Ventilator Interaction, Asynchrony, Patient-VentilatorArmsModified Delphi consensus survey
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Prashant NasaDepartment of Intensive Care, Amsterdam UMC, location 'AMC', Amsterdam, The Netherlands dr.prashantnasa@hotmail.com.ORCID http://orcid.org/0000-0003-1948-4060
Timur YurttasDivision of Anesthesiology, Rescue and Pain Medicine, HOCH Health Ostschweiz, St. Gallen, Switzerland.
Denise BattagliniAnesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID http://orcid.org/0000-0002-6895-6442
Stijn BlotDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0003-2145-0345
Ana Fernandez-BustamanteDepartment of Anesthesiology, University of Colorado System, Denver, Colorado, USA.
Marcelo Gama de AbreuDepartments of Intensive Care and Resuscitation and Outcomes ResearchDepartment of Cardiothoracic Anaesthesiology, Cleveland Clinic, Cleveland, Ohio, USA.
David M van MeenenDepartment of Intensive Care, Amsterdam UMC, location 'AMC', Amsterdam, The Netherlands.
Sheila Nainan MyatraDepartment of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Ary Serpa NetoDepartment of Intensive Care, Amsterdam UMC, location 'AMC', Amsterdam, The Netherlands.
Raymond OppongHealth Economics Unit, Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.ORCID http://orcid.org/0000-0002-0815-4616
Frederique PaulusDepartment of Intensive Care, Amsterdam UMC, location 'AMC', Amsterdam, The Netherlands.
Suresh RenukappaFaculty of Science and Engineering, University of Wolverhampton, Wolverhampton, UK.
Marcus J SchultzDepartment of Intensive Care, Amsterdam UMC, location 'AMC', Amsterdam, The Netherlands.
Arthur S SlutskyInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.
Sabrine N T HemmesDepartment of Intensive Care, Amsterdam UMC, location 'AMC', Amsterdam, The Netherlands.
PrECiSIOn–group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPostoperative pulmonary complications (PPCs) represent a significant cause of postoperative morbidity and even mortality. However, there is a lack of consensus regarding this composite endpoint, the definition of the individual components, classification and optimal outcome measures. This study aims to refine the PPCs composite framework by evaluating its construct validity, assessing the necessity and risks of a composite measure and exploring the feasibility of differentiating severity categories.

methodsA Delphi consensus process will be conducted, engaging an international multidisciplinary group of 30-40 panellists, including clinicians, researchers, patients, public representatives and health economists. Through iterative rounds, the study will seek agreement on the individual components of the PPCs composite. Additionally, consensus will establish a framework for a composite outcome measure based on a standardised severity classification, appropriate timeframes and weighted grading of PPCs. ANALYSIS: Consensus, defined by ≥75% concurrence in multiple choice questions or on Likert-scale statements, will be evaluated from round 2 onwards. Delphi rounds will be continued until all statements have reached stability of responses evaluated by χ ETHICS AND DISSEMINATION: The study will be conducted in strict compliance with the principles of the Declaration of Helsinki and will adhere to ACCORD guidance for reporting. Ethics approval has been obtained for this study from the University of Wolverhampton, UK (SOABE/202425/staff/3). Informed consent will be obtained from all panellists before the commencement of the Delphi process. The results of the study will be published in a peer-reviewed journal with the authorship assigned in accordance with ICMJE requirements. TRIAL REGISTRATION NUMBER: NCT06916598 (clinicaltrials.gov).

Indexed as

Lung DiseasesPostoperative ComplicationsConsensus Statements as TopicDelphi TechniqueHumansObservational Studies as TopicOutcome Assessment, Health CareResearch DesignAdult anaesthesiaANAESTHETICSDelphi Technique

Identifiers

PMID40829816
PMCPMC12366572

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.