Evidence map›Paper›PMID 40829815›Full record

Observational studyBMJ open2025

Considering the full care pathway in regional variation in paediatric otitis media treatment in the Netherlands: an observational study.

Vera de Weerdt, Christel van Dijk, Jako Burgers, Kati Gaspar, Karin Hek, Raphael J Hemler, Sjoerd Repping, Robert A Verheij, Hanna C Willems, Eric J E van der Hijden and 1 more

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vera de WeerdtHealth Economics, Vrije Universiteit, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0003-3644-620X
Christel van DijkNational Healthcare Institute Diemen Netherlands, Diemen, the Netherlands.
Jako BurgersNederlands Huisartsen Genootschap, Utrecht, Utrecht, the Netherlands.ORCID http://orcid.org/0000-0002-6040-4221
Kati GasparCPB Netherlands Bureau for Economic Policy Analysis, the Hague, the Netherlands.
Karin HekNIVEL, Netherlands Institute for Health Services Research, Utrecht, the Netherlands.
Raphael J HemlerOtholaringology, Gelre Hospitals, Apeldoorn, the Netherlands.
Sjoerd ReppingUniversity of Amsterdam, Amsterdam, the Netherlands.
Robert A VerheijNIVEL, Netherlands Institute for Health Services Research, Utrecht, the Netherlands.
Hanna C WillemsAmsterdam University Medical Centers, Amsterdam, the Netherlands h.c.willems@amsterdamumc.nl.
Eric J E van der HijdenHealth Economics, Vrije Universiteit, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0003-3359-2711
Xander KoolmanHealth Economics, Vrije Universiteit, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVentilation tube insertion for paediatric otitis media (POM), including acute otitis media (AOM) and otitis media with effusion (OME), has been signalled in the past for potential unwarranted treatment variation. Quality improvement initiatives, like Audit & Feedback (A&F), often ignore the care pathway when identifying such variation, possibly overestimating variation at a specific care step. To gain more insight into the effect of prior care steps, this study examined (1) the degree of regional variation in each step of the care pathway (general practitioner (GP) contacts, referrals and surgeries) and (2) investigated the effect of adjusting for prior care steps.

designObservational study using general practice electronic health record data linked to specialist claims data.

participants272 790 children ≤12 years with and without POM registered in 320 GP practices between 2017 and 2018. PRIMARY AND SECONDARY OUTCOMES: Using multilevel logistic regression, the degree of regional variation in each step of the POM care pathway was assessed by calculating the coefficient of variation (CV).The effect of adjusting for prior care steps was determined by estimating correlations between subsequent care steps and analysing the impact on the CV.

resultsRegional variation in POM treatment was larger in each subsequent step in the care pathway (CV POM GP contacts 0.110; referral 0.179; surgery 0.239). In regions with a higher proportion of children with frequent AOM/persistent OME, referral rates were higher (POM: OR: 1.06; 95% CI: 1.02 to 1.11) and surgical rates were higher (for OME only: OR: 1.08; 95% CI: 1.02 to 1.15). Regional variation in referrals and surgery decreased after adjusting for the regional frequent AOM/persistent OME rate (CV referrals POM 0.103 vs 0.128; CV surgery OME 0.047 vs 0.059).

conclusionsRegional variation is observed in GP contact rates for POM and is larger in referrals and surgeries. Adjusting for the proportion of frequent AOM/persistent OME significantly reduces regional variation in POM treatment. Future A&F should adjust for prior care processes and develop tailored interventions for quality improvement.

Indexed as

Critical PathwaysMiddle Ear VentilationOtitis MediaOtitis Media with EffusionPractice Patterns, Physicians'ChildChild, PreschoolElectronic Health RecordsFemaleGeneral PracticeHumansInfantMaleNetherlandsQuality ImprovementReferral and ConsultationPaediatric otolaryngologyPrimary CareQuality Improvement

Identifiers

PMID40829815
PMCPMC12366597

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.