Evidence map›Paper›PMID 40829666›Full record

ArticleProceedings. Biological sciences2025

Inflammaging is minimal among forager-horticulturalists in the Bolivian Amazon.

Jacob E Aronoff, Carrie L Jenkins, Angela R Garcia, Stephanie V Koebele, Suhail Ghafoor, Kate L Woolard, Mia Charifson, Ivan M Suarez, Daniel Eid Rodriguez, Bret Beheim and 11 more

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Incidence of dementia and mild cognitive impairment in two Indigenous Bolivian cohorts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Minimal Evidence of Inflammaging in Naturalistic Chimpanzee Populations.American journal of biological anthropology · 2026
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jacob E AronoffSchool of Human Evolution and Social Change; Center for Evolution and Medicine; Institute for Human Origins, Arizona State University, Tempe, AZ, USA.ORCID 0000-0002-1422-801X
Carrie L JenkinsSchool of Human Evolution and Social Change; Center for Evolution and Medicine; Institute for Human Origins, Arizona State University, Tempe, AZ, USA.ORCID 0000-0002-2235-2360
Angela R GarciaSchool of Life Sciences; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.
Stephanie V KoebeleSchool of Human Evolution and Social Change; Center for Evolution and Medicine; Institute for Human Origins, Arizona State University, Tempe, AZ, USA.ORCID 0000-0001-5502-2790
Suhail GhafoorCenter for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.
Kate L WoolardSchool of Human Evolution and Social Change; Center for Evolution and Medicine; Institute for Human Origins, Arizona State University, Tempe, AZ, USA.
Mia CharifsonDepartment of Population Health, Grossman School of Medicine, New York University, New York, NY, USA.
Ivan M SuarezFaculty of Medicine, Universidad Mayor de San Simon, Cochabamba, Cochabamba Department, Bolivia.
Daniel Eid RodriguezFaculty of Medicine, Universidad Mayor de San Simon, Cochabamba, Cochabamba Department, Bolivia.
Bret BeheimDepartment of Human Behavior, Ecology and Culture, Max-Planck-Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0000-0003-4653-3155
Daniel K CummingsEconomic Science Institute, Chapman University, Orange, CA, USA.
Paul L HooperEconomic Science Institute, Chapman University, Orange, CA, USA.
Thomas K KraftDepartment of Anthropology, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0002-0634-9233
Kenneth BuetowSchool of Life Sciences; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.
Caleb E FinchLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Maximilien FranckResearch Center on Aging, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada.ORCID 0009-0007-0431-2772
Alan A CohenRobert N. Butler Columbia Aging Center; Department of Environmental Health Sciences; Mailman School of Public Health, Columbia University, New York, NY, USA.ORCID 0000-0003-4113-3988
Jonathan StieglitzDepartment of Social and Behavioral Sciences, Toulouse School of Economics, Toulouse, Occitanie, France.ORCID 0000-0001-5985-9643
Michael GurvenDepartment of Anthropology, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID 0000-0002-5661-527X
Hillard KaplanEconomic Science Institute, Chapman University, Orange, CA, USA.ORCID 0000-0002-7398-7358
Benjamin C TrumbleSchool of Human Evolution and Social Change; Center for Evolution and Medicine; Institute for Human Origins, Arizona State University, Tempe, AZ, USA.ORCID 0000-0003-3201-0628

Funding

Agence Nationale de la RechercheNational Science FoundationNIA NIH HHS
6 · The paper itself

Abstract

An increase in chronic systemic inflammation in later life, termed inflammaging, is implicated in health risk. However, it is unclear whether inflammaging develops in all human populations, or if it is the product of environmental mismatch. We assessed inflammaging in Tsimane forager-horticulturalists of the Bolivian Amazon, using serum cytokines in a primarily cross-sectional sample (1134 samples from

Indexed as

CytokinesInflammationAdultAgedAged, 80 and overBoliviaCross-Sectional StudiesFemaleHumansIndians, South AmericanInterleukin-6MaleMiddle AgedCytokinesInterleukin-6ageingcytokinesinflammaginginflammationmismatch

Identifiers

PMID40829666
PMCPMC12364562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.