Evidence map›Paper›PMID 40829651›Full record

ArticleBiology letters2025

Caterpillars suppress nocifensive behaviours during the quiescent 'sphinx' state.

Gayathri Kondakath, Isabel M Messinger, Annushka Veliko-Shapko, Barry Trimmer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gayathri KondakathDepartment of Biology, Tufts University, Medford, MA, USA.ORCID 0000-0001-8416-1044
Isabel M MessingerDepartment of Biology, Tufts University, Medford, MA, USA.
Annushka Veliko-ShapkoDepartment of Biology, Tufts University, Medford, MA, USA.
Barry TrimmerDepartment of Biology, Tufts University, Medford, MA, USA.ORCID 0000-0003-1782-7373

Funding

Optical interrogation of neural circuits in ManducaR34NS118412 · NINDS · TUFTS UNIVERSITY MEDFORD · PI TRIMMER, BARRY A, YE, BING · 2020 to 2020
$608k
National Science Foundation Biological Science DirectorateNIH HHSNINDS NIH HHS R34 NS118412
6 · The paper itself

Abstract

Noxious (harmful) stimuli are detected by a specialized sensory process known as nociception, which typically evokes defensive behaviours to minimize tissue damage. While sensitization of nocifensive responses by intense or repetitive stimuli is well-documented in insects, instances of deliberate nociceptive suppression are relatively unexplored, particularly within natural behavioural contexts. Here, we describe a behavioural state in the tobacco hornworm (

Indexed as

Behavior, AnimalManducaNociceptionAnimalsLarvadefensive postureinsect larvaeManduca sextanociceptive modulationnociceptive tolerancepain

Identifiers

PMID40829651
PMCPMC12364565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.