ArticleJournal of psychosomatic research2025
Personality nuances and mortality risk: A coordinated analysis of four longitudinal samples.
Article in Journal of psychosomatic research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Personality nuances and inflammation: A coordinated analysis of six samples.Psychoneuroendocrinology · 2026Pooled it
- Personality and mortality risk: A systematic review and meta-analysis of longitudinal data.Journal of personality and social psychology · 2026Pooled it
- Definition and conceptual framework of the psychological domain of intrinsic capacity in healthy ageing: outcomes from the MOSAIC International Working Group.The journal of nutrition, health & aging · 2026Article
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Authors and funding
6 authors.
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Abstract
objectivePersonality nuances constitute the most specific level of the personality trait hierarchy and are often operationalized by individual questionnaire items. We examine whether these items are related to mortality to identify which specific personality characteristics are most related to length of life.
methodParticipants (N > 22,000) from the Health and Retirement Study, the Midlife in the United States Study, the National Social Life, Health, and Aging Project, and the National Health and Aging Trends Study completed 26-, 25-, 21- or 10-item measures of the Big Five personality traits using the Midlife Development Inventory. Mortality was tracked between 6 and 28 years.
resultsAcross most samples and meta-analyses, higher neuroticism domain and item scores were related to a higher mortality risk, whereas higher extraversion, agreeableness, and conscientiousness domain and item scores were associated with a lower mortality risk. Less consistent associations were found for the openness domain and items. The extraversion item "active" had the strongest association with lower mortality risk (pooled hazard ratios [HR] = 0.79, 95 %CI = 0.73-0.85), followed by "lively" (extraversion), "organized", "responsible", "hardworking", and "thorough" (conscientiousness), and "helpful" (agreeableness) (HRs range from 0.87 to 0.91). These associations were partially accounted for by clinical, behavioral, and psychological factors.
conclusionThis research deconstructs the five broad domains to identify the nuances most related to longevity. Specific personality items have replicable associations with mortality but little incremental predictive power compared to the corresponding domain. Still, the aggregated predictive value of items was stronger compared to the five broad personality domains.
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