Evidence map›Paper›PMID 40828985›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2025

Noninstrumented Posterolateral Lumbar Fusions Continue to Fade Relative to Instrumented Posterolateral Approaches for Lumbar Degenerative Spondylolisthesis Over the Past Decade.

Albert H Lee, Wesley Day, Siddhartha Lavu, Alexandros F Pappajohn, Michael J Gouzoulis, Jonathan N Grauer

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Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Albert H LeeFrom the Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT (Mr. Lee, Mr. Lavu, Mr. Pappajohn, Mr. Gouzoulis, and Dr. Grauer), and the Albert Einstein College of Medicine, Bronx, NY (Mr. Day).
Wesley Day
Siddhartha Lavu
Alexandros F Pappajohn
Michael J Gouzoulis
Jonathan N GrauerORCID 0000-0002-2626-7278

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough posterolateral lumbar fusions (PLFs) were historically routinely performed without instrumentation, instrumentation has become ubiquitous in this setting. Recent assessments of noninstrumented PLFs practices are lacking.

methodsLumbar degenerative spondylolisthesis patients undergoing noninstrumented or instrumented single-level PLFs (with or without interbody) were identified from 2012 to 2022 M170 Ortho PearlDiver. Univariable analysis identified differences in patient characteristics. Yearly utilization trends were tracked and analyzed using simple linear regression/overall F-tests. Ninety-day postoperative adverse outcomes were compared using multivariable logistic regression with 4:1 matching for patient age, sex, and Elixhauser comorbidity index. Five-year lumbar revision surgery rates were assessed using Kaplan-Meier survival analyses and log-rank tests.

resultsA total of 117,796 (95.8%) instrumented and 5147 (4.2%) noninstrumented PLF lumbar degenerative spondylolisthesis patients were identified. Noninstrumented PLFs declined from 5.52% to 3.49% from 2012 to 2022 (P < 0.001). These were more common in older, male, osteoporotic patients, varied by insurance and region, and were more often performed by orthopaedic surgeons. After matching, no notable differences were found between instrumented versus noninstrumented cases in 90-day aggregated adverse events or 5-year lumbar revision surgery rates. DISCUSSION: For lumbar degenerative spondylolisthesis, noninstrumented fusion represents a small and declining percentage of PLFs over the past decade, with usage varied by clinical and nonclinical patient characteristics. No differences were found in 90-day aggregated postoperative adverse events and 5-year lumbar revision surgery rates, suggesting that instrumentation can be safely performed and that both approaches had similarly durable results. These findings support considering noninstrumented PLFs in select cases when the safety, utility, or cost-benefit of instrumentation is questioned.

Indexed as

Lumbar VertebraeSpinal FusionSpondylolisthesisAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsReoperationRetrospective Studies

Identifiers

PMID40828985
PMCPMC12366972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.