ArticleMedical oncology (Northwood, London, England)2025
Anticancer efficacy of nerolidol, cyclophosphamide, and their combination against breast cancer cell line MCF-7.
Article in Medical oncology (Northwood, London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Role of Plant-Derived Antioxidants in Oxidative Stress-Associated Myocardial Infarction: Structure-Activity Relationship (SAR)-Based Mechanistic Insights.Molecules (Basel, Switzerland) · 2026Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In cancer, chemotherapeutic agents like cyclophosphamide (CP), is the most frequently used drug but the side effects caused by it, limits it's application. Therefore, creation of anticancer medicines with high efficacy and no or minimum side effects is a priority. In recent times, research on natural bioactive has been increased since they are efficient, safe, and economical. We earlier proved that Nerolidol (NER), a naturally derived sesquiterpene alcohol is a natural bioactive compound that could significantly reduce the CP-induced organ toxicities in Swiss albino mice. Thus, in this study, we intended to evaluate the anti-cancer property of NER alone and its potentiating effect in combination with CP in Michigan Cancer Foundation-7 (MCF-7) breast cancer cell line. MCF-7 is one of the most extensively used human breast cancer cell line, primarily because it closely resembles estrogen receptor-positive (ER
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.