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ReviewStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2025

Potential prognostic role of the

Lorena Draghini, Sara Costantini, Edy Ippolito, Francesca De Felice, Angela Caroli, Federico Navarria, Federica Piccolo, Bruno Fionda, Vitaliana De Sanctis, Gabriella Macchia and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lorena DraghiniSanta Maria Hospital, Radiation Oncology Center, Terni, Italy. l.draghini@aospterni.it.
Sara CostantiniSanta Maria Hospital, Radiation Oncology Center, Terni, Italy.
Edy IppolitoOperative Resesrch Unit of Radiation Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Francesca De FelicePoliclinico Umberto I, Department of Radiological, Oncological and Pathological Sciences, Radiation Oncology, Sapienza University of Rome, Rome, Italy.
Angela CaroliCentro di Riferimento Oncologico, Istituto di Ricovero e Cura a Carattere Scientifico, SOC Oncologia Radioterapica, Aviano, Italy.
Federico NavarriaCentro di Riferimento Oncologico, Istituto di Ricovero e Cura a Carattere Scientifico, SOC Oncologia Radioterapica, Aviano, Italy.
Federica PiccoloOspedale di Circolo e Fondazione Macchi, Department of Radiotherapy, ASST dei Sette Laghi, Varese, Italy.
Bruno FiondaDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, U.O.C. Radioterapia Oncologica, Rome, Italy.
Vitaliana De SanctisDepartment of Medicine and Surgery and Translational Medicine, S. Andrea Hospital, Radiotherapy Oncology, Sapienza University of Rome, Rome, Italy.
Gabriella MacchiaRadiation Oncology Unit, Responsible Research Hospital, Campobasso, Molise, Italy.
Lisa VicenziRadiation Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn locally advanced cervical cancer (LACC), chemoradiotherapy (CRT) represents the standard of care. The aim of this narrative review is to investigate the prognostic role of metabolic response of

methodsWe reviewed the literature according to the PRISMA guidelines to identify studies up to December 2023. The literature search was performed on PubMed and Scopus, using the following combination of medical subject headings (MeSH) and keywords "Uterine Cervical Neoplasms", "

resultsAfter the literature research, 9 studies fulfilled the inclusion criteria and were included in this review. Metabolic response after radical CRT treatment was significantly related to better clinical outcomes and to lower local relapse. Incomplete metabolic response could be considered a predictive factor for distant metastasis and cancer related deaths.

conclusionCurrent data highlight the potential role of metabolic response of

Indexed as

ChemoradiotherapyFluorodeoxyglucose F18Positron Emission Tomography Computed TomographyUterine Cervical NeoplasmsFemaleHumansNeoplasm Recurrence, LocalPrognosisRadiopharmaceuticalsFluorodeoxyglucose F18Radiopharmaceuticals18F-FDG PET/CTLocally advanced cervical cancerMetabolic responseRadiochemotherapyReview

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.