ArticleDermatologie (Heidelberg, Germany)2026
[Multiple squamous cell carcinomas arising in linear porokeratosis].
Article in Dermatologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This case report discusses a 58-year-old patient with linear porokeratosis who subsequently developed cutaneous squamous cell carcinoma. Porokeratosis is a rare keratinisation disorder which carries a risk of malignant transformation. The patient initially presented with recurrent erosions and ulcerations. After initial reluctance of the patient to seek medical help, biopsies confirmed squamous cell carcinoma in several lesions. These were successfully excised and the patient opted for secondary wound healing. Due to its potential for malignancy, porokeratosis often requires diligent monitoring. It typically features hyperkeratotic lesions that can progress over time. Although there are various treatment options for porokeratosis, long-term efficacy is limited. This case emphasises the importance of early biopsy in chronic, nonhealing wounds, as well as the need for patient education and regular follow-up to effectively manage the risk of malignancy.
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