Evidence map›Paper›PMID 40828349›Full record

ArticleAdvances in therapy2025

Epidemiology Landscape and Impact of Overweight and Obesity in Adults: Multi-country Results from the IMPACT-O Study.

Esther Artime, Erik Spaepen, Sarah Zimner-Rapuch, Anastasia Lampropoulou, Atif Adam, Xiaoyu Lin, Mengyuan Shang, Sarah Seager, Carel W Le Roux, Dror Dicker

Erratum issuedAbstract readMulticenter Study
In one paragraph

Article in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Trends in Diagnosing Obesity: The CALOR Study.Obesity (Silver Spring, Md.) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Esther ArtimeEli Lilly and Company, Indianapolis, IN, USA. artime_esther@lilly.com.
Erik SpaepenHaaPACS GmbH, Schriesheim, Germany.
Sarah Zimner-RapuchEli Lilly and Company, Indianapolis, IN, USA.
Anastasia LampropoulouEli Lilly and Company, Indianapolis, IN, USA.
Atif AdamIQVIA Inc., London, UK.
Xiaoyu LinIQVIA Inc., London, UK.
Mengyuan ShangIQVIA Inc., London, UK.
Sarah SeagerIQVIA Inc., London, UK.
Carel W Le RouxDiabetes Complications Research Centre, Conway Institute, University College Dublin, Dublin, Ireland.
Dror DickerDepartment of Medicine and Obesity Clinic, Rabin Medical Center (HaSharon Hospital), Petah Tikva, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo estimate the recording rates and impact of overweight/obesity across selected countries in Europe and Asia-Pacific.

methodsIMPACT-O was a retrospective cohort study of electronic medical records and claims databases from France, Germany, Italy, Spain, the UK, Australia, and Japan. Recording levels and the number of adults with overweight/obesity [based on diagnostic codes and/or body mass index (BMI)] during 2018-2022 were estimated. BMI thresholds/categories and obesity-related complications (ORCs) were described for adults with ≥ 1 BMI record of ≥ 25.0 kg/m

resultsThe number of active subjects across databases ranged from 1,203,674 to 22,413,902. BMI was recorded for 4.8-38.9% of active patients. The number of adults with overweight/obesity ranged from 3.5% in Australia to 24.9% in the UK. The percentage of individuals with BMI > 25 to < 30 kg/m

conclusionOnly a small proportion of people with overweight/obesity are formally diagnosed in healthcare databases. Most present with ≥ 1 ORC, commonly hypertension, dyslipidemia, depression, and type 2 diabetes.

Indexed as

ObesityOverweightAdultAgedBody Mass IndexDatabases, FactualEuropeFemaleHumansHypertensionMaleMiddle AgedRetrospective StudiesCardiovascular diseaseDatabasesEpidemiologyObesityOverweight

Identifiers

PMID40828349
PMCPMC12474581

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.