ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2025
Coronary flow and resistance patterns indexed by subtended myocardial mass in coronary microvascular dysfunction.
Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Quantification of Myocardial Mass by Cardiac Computed Tomography: A Tool for Preprocedural Planning of Coronary Revascularization.Journal of the American Heart Association · 2025Article
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14 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with coronary microvascular dysfunction (CMD) exhibit impaired vasodilatation of the microcirculation. This manifests as reduced microvascular resistance reserve (MRR) due to either increased resting flow (Q
aimsWe investigated the relationship between subtended myocardial mass, microvascular resistance, and coronary flow to determine whether the disturbed resistance and flow patterns seen in CMD persisted after indexing by subtended myocardial mass.
methodsWe recruited 100 patients with angina with non-obstructive coronary arteries who underwent coronary computed tomography angiography to quantify vessel-specific subtended myocardial mass. Continuous intracoronary thermodilution was used to quantify absolute coronary flow and microvascular resistance, both at rest and during hyperaemia. Among patients with an MRR <3.0, hyperaemic microvascular resistance (R
resultsMass and flow were analysed in 100 patients in the left anterior descending artery. The mean subtended myocardial mass in the structural CMD group (47.00±13.83 grams) was significantly lower than in the control group (59.64±21.69 grams; p=0.027), with no significant difference between the control group and the functional CMD group (53.75±13.99 grams; p=0.339). After indexing by the subtended mass, patients with structural CMD still had higher R
conclusionsDespite significantly lower subtended mass, patients with structural CMD exhibit abnormal indexed R
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