Evidence map›Paper›PMID 40828297›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2025

Harnessing Egocentric Networks to Inform an Enhanced Social Network Strategy in a Southern US "Ending the HIV Epidemic" Region.

Guozheng Yang, Ian Dale, Meagan Zarwell, Jesse Strunk Elkins, Alicia Diggs, Carol Golin, Feng-Chang Lin, Ann M Dennis

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guozheng YangDivision of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Ian DaleDivision of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Meagan ZarwellDepartment of Epidemiology and Community Health, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC.
Jesse Strunk ElkinsDepartment of Epidemiology and Community Health, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC.
Alicia DiggsCenter for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Carol GolinCenter for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Feng-Chang LinDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Ann M DennisDivision of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.ORCID 0000-0003-0687-9661

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Rapid Response to Incident HIV Infection through Social Network Strategies and Molecular Epidemiology to Inform Partner ServicesR01AI169602 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ann Dennis · 2022 to 2026
$3.6M
National Institute of Allergy and Infectious Diseases R01AI169602NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI169602
6 · The paper itself

Abstract

backgroundThe HIV epidemic in the United States disproportionately affects sexual and gender minority (SGM) communities. Social networks shape health behaviors. Understanding the structure and dynamics of SGM networks could enhance engagement with HIV-related services.

methodsWe analyzed egocentric social networks of SGM individuals in Charlotte, North Carolina, who engaged in HIV-related services. Participants (egos) identified social connections (alters) from the past 6 months. Networks were stratified based on the size of the ego's sexual network (0-1 vs. ≥2), defined as the subset of alters with reported sexual partnerships, to assess differences in structure and support dynamics.

resultsAmong 51 participants, 294 alters were reported. Networks with 0-1 sexual partners were smaller, more connected, and exhibited greater demographic diversity. These egos had stronger ties with their alters (n = 141), who were more likely to provide social and health-related support. By contrast, networks with ≥2 sexual partners (n = 153 alters) were less cohesive, exhibited lower network density and global efficiency (capacity for efficient information sharing), and sexual partners were less likely to offer health support.

conclusionsNetwork-based interventions must account for pre-existing social support structures. Tight-knit, supportive networks may reinforce health norms and serve as conduits for intervention messaging, while individuals with larger, less connected sexual networks may require additional support to mobilize their networks effectively. Tailoring interventions to network dynamics could enhance HIV service uptake and improve health outcomes in SGM populations.

Indexed as

EpidemicsHIV InfectionsSexual and Gender MinoritiesSocial NetworkingSocial SupportAdultFemaleHumansMaleMiddle AgedNorth CarolinaSexual BehaviorSexual PartnersYoung AdultHIV-1public healthsexual and gender minoritiessexual partnerssocial networking

Identifiers

PMID40828297
PMCPMC12664677

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.