Evidence map›Paper›PMID 40828264›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Anti-GABAB receptor encephalitis combined with autoimmune polyendocrine gland syndrome.

Yi He, Fahang Yi, Ping Tang, Kaiqiang Xiao, Liang Wang

Abstract readCase Reports
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi HeDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Fahang YiDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ping TangDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Kaiqiang XiaoDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Liang WangDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. wang0128_0@163.com.ORCID http://orcid.org/0000-0002-0606-561X

Funding

High-Level Medical Reserved Personnel Training Project of Chongqing 2020GDRC019
6 · The paper itself

Abstract

Anti-GABAB receptor encephalitis coexistence with autoimmune polyendocrine syndrome (APS) has not been reported. We present the first case of anti-GABAB receptor encephalitis coexisting with APS type III. A 64-year-old male presented with recurrent convulsions with loss of consciousness. Diagnostic evaluation revealed positive anti-GABAB receptor antibodies, elevated HbA1cand fasting blood glucose, and glutamic aciddecarboxylase antibodies (GAD-Ab), hypothyroidism with positive thyroglobulin and peroxidase antibody. The patient demonstrated complete diagnostic criteria for both anti-GABAB receptor encephalitis and APS type III. A Combination therapy with pulse corticosteroids, intravenous immunoglobulin, levothyroxine, and insulin achieved significant clinical improvement. The findings expand the spectrum of autoimmune overlap syndromes and highlight diagnostic challenges in patients presenting with concurrent neurological and endocrine dysfunction.

Indexed as

EncephalitisPolyendocrinopathies, AutoimmuneAutoantibodiesHumansMaleMiddle AgedAutoantibodiesAnti-GABAB receptor encephalitisAutoimmune encephalitisAutoimmune polyendocrine gland syndromeCase report

Identifiers

PMID40828264

What OpenQuestion holds

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