Evidence map›Paper›PMID 40828206›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2025

Chlorophyllin-based Photodynamic Inactivation against Candidozyma auris planktonic cells and dynamic biofilm.

Annette Wimmer, Linda Jernej, Jun Liu, Michael Fefer, Kristjan Plaetzer

Abstract read
PubMed Publisher
In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. StudyingPharmaceuticals (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annette Wimmer *Laboratory of Photodynamic Inactivation of Microorganisms, Department of Biosciences and Medical Biology, University of Salzburg, 5020, Salzburg, Austria.
Linda JernejLaboratory of Photodynamic Inactivation of Microorganisms, Department of Biosciences and Medical Biology, University of Salzburg, 5020, Salzburg, Austria.
Jun LiuSuncor Energy Inc, Calgary, AB, Canada.
Michael FeferSuncor Energy Inc, Calgary, AB, Canada.
Kristjan PlaetzerLaboratory of Photodynamic Inactivation of Microorganisms, Department of Biosciences and Medical Biology, University of Salzburg, 5020, Salzburg, Austria. kristjan.plaetzer@plus.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candidozyma auris likely gained thermotolerance as a result of climate change and emerged from its origin in Indian wetlands to a severe healthcare threat because of its resistance to common antifungals and antiseptics in only a few decades. This development identifies the yeast as a perfect example for the relevance of the One Health concept for human well-being. Here, we compare the effectiveness of Photodynamic Inactivation (PDI) based on the economic and ecofriendly natural photosensitizer sodium-magnesium-chlorophyllin (Chl) to that of a synthetic chlorin e6 derivative carrying cationic moieties, B17-0024, suggesting both as alternative to common disinfectants against C. auris. Experiments were conducted on planktonic cells and-for the very first time-on dynamic biofilms using the CDC bioreactor. Treatment of planktonic cells with 50 µM Chl and blue light (395 nm, 7.5 J cm

Indexed as

BiofilmsChlorophyllidesPhotosensitizing AgentsPlanktonSaccharomycetalesLightMicrobial Sensitivity TestsPhotochemotherapyChlorophyllideschlorophyllinPhotosensitizing AgentsBlue lightCandida aurisCandidozyma aurisChlorophyllinDynamic biofilmOne healthPhotodynamic InactivationRed light

Identifiers

PMID40828206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.