Evidence map›Paper›PMID 40828124›Full record

ReviewThe Journal of investigative dermatology2025

A Comprehensive Review of GWASs of Human Hair Traits.

Carli D Needle, Anna L Brinks, Olivia D Perez, Jerry Shapiro, Kristen I Lo Sicco, Aristotelis Tsirigos, Lynn Petukhova

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of investigative dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carli D NeedleThe Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, New York, USA.
Anna L BrinksThe Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, New York, USA.
Olivia D PerezThe Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, New York, USA.
Jerry ShapiroThe Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, New York, USA.
Kristen I Lo SiccoThe Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, New York, USA.
Aristotelis TsirigosDivision of Precision Medicine, Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA; Applied Bioinformatics Laboratories, Office of Science and Research, NYU Grossman School of Medicine, New York, New York, USA.
Lynn PetukhovaThe Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, New York, USA; Department of Population Health, NYU Grossman School of Medicine, New York, New York, USA. Electronic address: Lynn.Petukhova@nyulangone.org.

Funding

Establishing the contributions of monogenic etiologies to hidradenitis suppurativapathogenesisR01AR080796 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Lynn Petukhova · 2023 to 2026
$2.1M
Identification of biologically relevant subtypes of hidradenitis suppurativaK01AR075111 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PETUKHOVA, LYNN · 2020 to 2024
$534k
NIAMS NIH HHS K01 AR075111NIAMS NIH HHS R01 AR080796
6 · The paper itself

Abstract

Hair traits are nonpathogenic features that vary among individuals. Unlike hair follicle (HF) diseases, which are rare in the population, hair traits can be measured in everyone. This facilitates the construction of large cohorts that are well-powered for gene discovery. GWASs identify genetic variants that are widely shared among people globally, providing knowledge with broad population relevance. We compile findings from hair trait GWASs to deepen our understanding of HF biology. In reviewing genetic factors that influence hair traits, we demonstrate overlap with disease genes, underscoring that genetic studies of traits improve our knowledge about health and disease.

Indexed as

Genome-Wide Association StudyHairHair DiseasesHair FollicleGenetic Predisposition to DiseaseHumansPhenotypeGWASsHair follicleHair follicle biologyHair traits

Identifiers

PMID40828124
PMCPMC12399957

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.