Evidence map›Paper›PMID 40828089›Full record

ArticleChemical research in toxicology2025

Liver and Intestinal Fatty Acid Binding Proteins Are Not Critical for Perfluorooctanesulfonate (PFOS) Tissue Distribution and Elimination in Mice.

Seyed Mohamad Sadegh Modaresi, Jitka Becanova, Simon Vojta, Sangwoo Ryu, Emily M Kaye, Juliana Agudelo, Anastasia Diolintzi, Olga Skende, Judith Storch, Fabian C Fischer and 1 more

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Seyed Mohamad Sadegh ModaresiDepartment of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island 02881, United States.
Jitka BecanovaGraduate School of Oceanography, University of Rhode Island, Kingston, Rhode Island 02881, United States.ORCID 0000-0002-3091-1054
Simon VojtaGraduate School of Oceanography, University of Rhode Island, Kingston, Rhode Island 02881, United States.
Sangwoo RyuDepartment of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island 02881, United States.
Emily M KayeDepartment of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island 02881, United States.
Juliana AgudeloDepartment of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island 02881, United States.
Anastasia DiolintziDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey 08901, United States.
Olga SkendeDepartment of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island 02881, United States.
Judith StorchDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey 08901, United States.
Fabian C FischerDepartment of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island 02881, United States.ORCID 0000-0002-9511-0506
Angela SlittDepartment of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island 02881, United States.

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Christopher Lee Hemme · 2012 to 2026
$63.6M
Sources, Transport, Exposure & Effects of PFAS (STEEP) Center - RENEWALP42ES027706 · NIEHS · UNIVERSITY OF RHODE ISLAND · PI Rainer Lohmann · 2017 to 2026
$18.9M
Supplement to DK-38389 Lipid Transport in the IntestineR01DK038389 · NIDDK · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI SAMPATH, HARINI, STORCH, JUDITH · 1992 to 2025
$8.6M
The role of albumin and other serum factors in Per- and polyfluoroalkyl substance (PFAS) accumulation and toxicityR01ES037367 · NIEHS · UNIVERSITY OF RHODE ISLAND · PI Angela L Slitt · 2025 to 2026
$952k
NIDDK NIH HHS R01 DK038389NIEHS NIH HHS P42 ES027706NIEHS NIH HHS R01 ES037367NIGMS NIH HHS P20 GM103430
6 · The paper itself

Abstract

Perfluorooctanesulfonate (PFOS) is a persistent environmental pollutant in the per- and polyfluoroalkyl substances (PFAS) class, known to accumulate in the liver and trigger hepatotoxicity. While

Indexed as

Alkanesulfonic AcidsFatty Acid-Binding ProteinsFluorocarbonsIntestinal MucosaLiverAnimalsMaleMiceMice, Inbred C57BLMice, KnockoutTissue DistributionAlkanesulfonic AcidsFatty Acid-Binding ProteinsFluorocarbonsperfluorooctane sulfonic acid

Identifiers

PMID40828089
PMCPMC12442221

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.