Evidence map›Paper›PMID 40827914›Full record

ArticleJournal of virology2025

ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid.

Aila Gulijiahani, Jun Arii, Vuk Isakovic, Jing Rin Huang, Yasushi Kawaguchi, Yasuko Mori

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aila Gulijiahani *Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.ORCID 0009-0002-6616-1192
Jun Arii *Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.ORCID 0000-0002-1689-4016
Vuk IsakovicDivision of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
Jing Rin HuangDivision of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
Yasushi KawaguchiDivision of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan.ORCID 0000-0001-8232-6925
Yasuko MoriDivision of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.ORCID 0000-0002-6595-8522

Funding

Japan Agency for Medical Research and Development 20wm0325005hJapan Agency for Medical Research and Development (AMED) 22gm6410022hJapan Society for the Promotion of Science Grants for Scientific ResearchMinistry of Education, Culture, Science, Sports and Technology of Japan 19H05286Ministry of Education, Culture, Science, Sports and Technology of Japan LEADERMSD Life Science Foundation Research grantShionogi Infectious Disease Research Promotion Foundation Research grantThe Chemo-Sero-Therapeutic Research Institute Research grantThe Waksman Foundation of Japan Research grant
6 · The paper itself

Abstract

Herpesviruses replicate their genomes and package them into capsids within the host cell nucleus. These capsids must then translocate from the nucleus to the cytoplasm through a process designated nuclear egress. The virus-encoded nuclear egress complex (NEC), consisting of a nuclear matrix protein and a nuclear membrane protein, plays a crucial role in this process. Although the role of NEC for nucleo-cytoplasmic transport of capsids is conserved in

Indexed as

Cell NucleusEndosomal Sorting Complexes Required for TransportHerpesvirus 6, HumanNucleocapsidVirus ReleaseCapsidCell LineCytomegalovirusHEK293 CellsHumansNuclear EnvelopeVirus ReplicationEndosomal Sorting Complexes Required for TransportESCRT-IIIherpesvirusesHHV-6nuclear egress

Identifiers

PMID40827914
PMCPMC12456135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.