Evidence map›Paper›PMID 40827878›Full record

ArticleApplied and environmental microbiology2025

PlyCYU endolysin targeting

Sakunrat Ubonprasert, Wachiraporn Wachiradusit, Wichai Pornthanakasem, Warangkhana Songsungthong, Aritsara Jaruwat, Sasina Premjaichon, Tanaporn Uengwetwanit, Rinrada Suntivich, Konrawee Thananon, Kanyarat Suksomjaisaman and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Sakunrat Ubonprasert *National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.
Wachiraporn Wachiradusit *National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.
Wichai PornthanakasemNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.
Warangkhana SongsungthongNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.ORCID 0000-0001-7824-5153
Aritsara JaruwatNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.
Sasina PremjaichonSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wang Chan District, Rayong, Thailand.
Tanaporn UengwetwanitNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.
Rinrada SuntivichNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.
Konrawee ThananonDepartment of Biochemistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Kanyarat SuksomjaisamanDepartment of Biochemistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Jeerus SucharitakulDepartment of Biochemistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Chutathip PuypromCenter of Excellence for Molecular Biology and Genomics of Shrimp, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Tamonwan LotangchanintraCenter of Excellence for Molecular Biology and Genomics of Shrimp, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Kanokwan SalamtehCenter of Excellence for Molecular Biology and Genomics of Shrimp, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Kittikhun WangkanontCenter of Excellence for Molecular Biology and Genomics of Shrimp, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Channarong RodkhumCenter of Excellence in Fish Infectious Diseases (CE FID), Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Wonnop VisessanguanSiriraj Metabolomics and Phenomics Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Pimchai ChaiyenSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wang Chan District, Rayong, Thailand.
Penchit ChitnumsubNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.ORCID 0000-0001-5920-3708
Ubolsree LeartsakulpanichNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Khlong Luang, Pathum Thani, Thailand.ORCID 0000-0002-4011-7217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophage endolysins are attractive alternatives to antibiotics owing to their rapid action, host specificity, and unlikeliness of resistance development. Here, bioinformatic analysis of

Indexed as

AmidohydrolasesHexosaminidasesPeptide HydrolasesProtein MultimerizationStreptococcus agalactiaeAmino Acid SequenceBiocatalysisCysteineGenetic VariationHistidineKineticsProtein Structure, TertiaryRecombinant ProteinsSequence AlignmentSubstrate SpecificityAmidohydrolasesCysteineHexosaminidasesHistidinePeptide HydrolasesRecombinant Proteinsamidase_5antibiotic alternativeCHAP domainendolysinStreptococcus agalactiae

Identifiers

PMID40827878
PMCPMC12442389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.