Evidence map›Paper›PMID 40827771›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2025

Coacervate Vesicles as Adaptive Platforms for Synthetic Biology and Smart Materials.

Francesco Vicentini, Federica Battistin, Pierangelo Gobbo

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francesco VicentiniDepartment of Chemical and Pharmaceutical Sciences, University of Trieste, Via L. Giorgieri 1, Trieste, 34127, Italy.ORCID https://orcid.org/0009-0009-6551-1534
Federica BattistinDepartment of Chemical and Pharmaceutical Sciences, University of Trieste, Via L. Giorgieri 1, Trieste, 34127, Italy.ORCID https://orcid.org/0000-0002-6518-9129
Pierangelo GobboDepartment of Chemical and Pharmaceutical Sciences, University of Trieste, Via L. Giorgieri 1, Trieste, 34127, Italy.ORCID https://orcid.org/0000-0003-2575-5816

Funding

HORIZON EUROPE European Research Council 101039578National Recovery and Resilience Plan, Next Generation EU 2022285HC5_002National Recovery and Resilience Plan, Next Generation EU CN00000041
6 · The paper itself

Abstract

Coacervate vesicles represent a versatile and emerging class of protocells that combine the dynamic properties of coacervate microdroplets with the structural advantages of membrane-bound systems. Leveraging features such as selective molecular uptake, enhanced reactivity, and dynamicity, they offer a promising platform for both fundamental research and technological applications in synthetic biology. In this concept, we introduce a classification of coacervate vesicles based on their formation mechanisms and energetic landscapes, highlighting how their formation routes give rise to protocells with distinct structural and dynamic properties. Furthermore, we explore how these features translate into potential applications, including artificial life-like systems, complex communication networks, adaptive soft materials, and smart drug-delivery platforms. While the field is still in its infancy, the simplicity, versatility, and programmability of coacervate vesicles position them as a powerful framework for engineering next-generation synthetic life-like systems.

Indexed as

Artificial CellsSynthetic BiologyDrug Delivery Systemsbottom‐up synthetic biologycoacervateout‐of‐equilibriumprotocellvesicle

Identifiers

PMID40827771
PMCPMC12462236

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.