Evidence map›Paper›PMID 40827743›Full record

ArticleJournal of the American Chemical Society2025

Accelerating the Pace of Oxygen Evolution Reaction Catalyst Discovery through Megalibraries.

Jin Huang, Zhe Wang, Jiashun Liang, Xiao-Yan Li, Jacob Pietryga, Zihao Ye, Peter T Smith, Alp Kulaksizoglu, Connor R McCormick, Jaerim Kim and 8 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Data- and Theory-Guided Design of Dual-Role V-Doped RuOAngewandte Chemie (International ed. in English) · 2026
    Article
  2. Article
  3. Synergistic Co-Doping of Barium and Cobalt Enables Stable and Active RuOAngewandte Chemie (International ed. in English) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jin HuangDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-2882-2634
Zhe WangDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Jiashun LiangDepartment of Energy, Environmental & Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, United States.ORCID 0000-0003-4328-1650
Xiao-Yan LiDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Jacob PietrygaInternational Institute for Nanotechnology, Evanston, Illinois 60208, United States.
Zihao YeDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0003-0616-5650
Peter T SmithDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Alp KulaksizogluInternational Institute for Nanotechnology, Evanston, Illinois 60208, United States.ORCID 0000-0002-6608-8151
Connor R McCormickDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Jaerim KimDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Bosi PengDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Zeyan LiuDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Ke XieDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0003-4220-272X
Steven B TorrisiEnergy & Materials Division, Toyota Research Institute, Los Altos, California 94022, United States.
Joseph H MontoyaEnergy & Materials Division, Toyota Research Institute, Los Altos, California 94022, United States.ORCID 0000-0001-5760-2860
Gang WuDepartment of Energy, Environmental & Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, United States.ORCID 0000-0003-0885-6172
Edward H SargentDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Chad A MirkinDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-6634-7627

Funding

TR&D Project 3: Photoacoustic Detection of Metal Fluxes at the Tissue LevelP41GM135018 · NIGMS · NORTHWESTERN UNIVERSITY · PI JACOBSEN, CHRIS JOHNSON, O'HALLORAN, THOMAS V · 2020 to 2024
$5.8M
Acquisition of a K2 Camera for Soft Matter Transmission Electron MicroscopyS10OD026871 · OD · NORTHWESTERN UNIVERSITY · PI GIANNESCHI, NATHAN CLAUDE · 2019 to 2019
$663k
An IC-ICP-MS for advanced speciation and metalomics analysisS10OD020118 · OD · NORTHWESTERN UNIVERSITY · PI O'HALLORAN, THOMAS V · 2015 to 2015
$268k
NIGMS NIH HHS P41 GM135018NIH HHS S10 OD020118NIH HHS S10 OD026871
6 · The paper itself

Abstract

Iridium (Ir) catalysts are essential for the acidic oxygen evolution reaction (OER) in proton-exchange membrane water electrolyzers (PEMWEs), but their high cost, scarcity, and geographical concentration limit large-scale adoption. In addition, the discovery of non-Ir alternatives is slow due to the vast design space possible. Here, a "megalibrary" is used to explore the catalytic activity of ∼156 million distinct nanostructures comprised of Ru, Co, Mn, and Cr to find alternatives to Ir catalysts for OER. Over 40 RuCoMnCr oxides, ranging from low to high activity, were selected, scaled to milligram levels, and studied for their catalytic performance. The activities measured within the megalibrary closely correlated (

Identifiers

PMID40827743
PMCPMC12685156

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.