ReviewPathology international2025
Primary Pulmonary Epithelial-Myoepithelial Carcinoma With Prominent Reactive Pneumocytes: Clinicopathological Insights Into a Rare Case and Literature Review.
Review in Pathology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Primary salivary gland-type tumors may rarely be accompanied by hyperplastic alveolar cells, a pattern referred to as pneumocytic adenomyoepithelioma (PAM). Most previously reported cases have relied solely on immunohistochemical findings. In this report, we present a case involving three distinct types of epithelial cell components, identified through dual immunohistochemical staining for p40/TTF-1, in addition to the detection of HRAS mutation using next-generation sequencing. The female patient, in her 70s, underwent left lower lobectomy after a chest CT scan revealed a 20 mm solid mass in the left lower lobe. The final histopathological diagnosis was a primary pulmonary epithelial-myoepithelial carcinoma (EMEC). This paper presents a case of a primary pulmonary EMEC exhibiting so-called PAM morphology and includes a brief review of the literature.
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