ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Iron Single-Atom Catalyzed N-Alkylation of Amines with Alcohols via Solvent-Free Borrowing Hydrogen Strategy.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Flow Chemistry as an Enabling Technology for Process-Intensified Amination Reactions: A Decadal Review.Molecules (Basel, Switzerland) · 2026Review
- Iron Single-Atom Catalyzed N-Alkylation of Amines with Alcohols via Solvent-Free Borrowing Hydrogen Strategy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
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12 authors.
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Abstract
Industrial hydrogenation is a pivotal process in chemical synthesis. However, it has significant drawbacks, including high cost, safety risks associated with the use of molecular hydrogen gas, and substantial energy demands due to the need for elevated temperatures and pressures to achieve satisfactory yields. The borrowing hydrogen synthesis, which enables the transfer of hydrogen between molecules, offers a promising approach for green, one-pot synthesis of industrially important chemicals and intermediates. Despite its potential, the broad application remains limited due to the reliance on toxic solvents, expensive noble metal catalysts, and the still restricted efficiency and substrate scope. In this study, the first solvent-free strategy for the N-alkylation of amines with alcohols is presented, employing an N-doped graphene-supported Fe single-atom catalyst (Fe
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