Evidence map›Paper›PMID 40827525›Full record

ArticleJournal of clinical periodontology2025

Using Dental Register Information and Questionnaire Data to Assess Periodontitis in Large Cohort Studies.

Peter Persson, Magnus Bladh, Stanley Teleka, Aleksandar Milosavljevic, Nils Gustafsson, Eva Levring Jäghagen, Björn Klinge, Kushan De Silva, Niko Vähäsarja, Kåre Buhlin and 5 more

Abstract readComparative Study
In one paragraph

Article in Journal of clinical periodontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Peter PerssonDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.ORCID 0009-0001-7573-3220
Magnus BladhOral and Maxillofacial Radiology, Department of Odontology, Umeå University, Umeå, Sweden.
Stanley TelekaDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.ORCID 0000-0002-9343-8399
Aleksandar MilosavljevicFaculty of Odontology, Malmö University, Malmö, Sweden.ORCID 0000-0001-9449-9073
Nils GustafssonOral and Maxillofacial Radiology, Department of Odontology, Umeå University, Umeå, Sweden.ORCID 0000-0003-1120-8993
Eva Levring JäghagenOral and Maxillofacial Radiology, Department of Odontology, Umeå University, Umeå, Sweden.
Björn KlingeFaculty of Odontology, Malmö University, Malmö, Sweden.
Kushan De SilvaHelmholtz Institute for Metabolic, Obesity, and Vascular Research, Helmholtz Munich, Leipzig, Germany.
Niko VähäsarjaDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Kåre BuhlinDepartment of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.
Peter NilssonDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Marju Orho-MelanderDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Olle MelanderDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.ORCID 0000-0002-2581-484X
Aron Naimi-AkbarFaculty of Odontology, Malmö University, Malmö, Sweden.
Daniel JönssonDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.ORCID 0000-0001-8298-539X

Funding

Albert Påhlsson Foundation 20210036CO Henrikson FoundationCrafoordska StiftelsenKempe FoundationOral Health-Related Research by Region Skåne OFRS 1010651Oral Health-Related Research by Region Skåne OFRS 422361Oral Health-Related Research by Region Skåne OFRS 512951Oral Health-Related Research by Region Skåne OFRS 567711Oral Health-Related Research by Region Skåne OFRS 655561Oral Health-Related Research by Region Skåne OFRS 752071Oral Health-Related Research by Region Skåne OFRS 853031Oral Health-Related Research by Region Skåne OFRS 931171Oral Health-Related Research by Region Skåne OFRS 968144Public Dental Service of SkåneSwedish Dental Society 396174510Swedish Research Council 2018-02760Swedish State through the ALF agreement 2021-YF0052Swedish State through the ALF agreement 2024-YF0013The Swedish Heart Lung Foundation 20230597TUA Research Funding Västerbotten County Council 7003195TUA Research Funding Västerbotten County Council 7004491
6 · The paper itself

Abstract

aimPeriodontitis proxy variables enable an expansion of periodontal research. The study aimed to estimate the validity of questionnaire items and registry data in relation to Stage III-IV periodontitis and having 50% bone loss.

methodsMalmö Offspring Dental Study (MODS) participants (995) filled out questionnaires and underwent periodontal and panoramic radiography examinations. The questionnaire items, number of periodontal treatment procedures (PTP) in the Dental Health Register (DHR), and number of teeth with ≥ 6 mm probing depth in the Swedish Quality Register for Caries and Periodontal Disease (SKaPa) were evaluated as proxies for severe periodontitis. Stage III-IV periodontitis was the primary reference standard.

resultsFor PTP-based severe periodontitis proxy in DHR, positive predictive value (PPV) was 88% and negative predictive value (NPV) 87% for Stage III-IV. The SKaPa-based proxy showed poor positive predictive values (PPVs, < 70%), but similar area under the curve (AUC), 0.74, compared with the DHR data (AUC 0.76). Sensitivity was < 70%, and specificity > 90% for the DHR and SKaPa proxies. Identification of cases with periodontitis by questionnaire combined with the demographic variables age, sex, smoking habits and education yielded good discriminatory ability (AUC > 0.75).

conclusionRegister-based data can effectively identify individuals with severe periodontitis in large cohort studies, thereby advancing periodontal research.

Indexed as

PeriodontitisRegistriesAdultAgedAge FactorsAlveolar Bone LossCohort StudiesEducational StatusFemaleHumansMaleMiddle AgedPeriodontal PocketRadiography, PanoramicSensitivity and SpecificitySex FactorsDental Health Registerepidemiologyperiodontitisself‐reportedSwedish Quality Register for Caries and Periodontal Disease

Identifiers

PMID40827525
PMCPMC12531359

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.