Evidence map›Paper›PMID 40827491›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2026

Kinematic alignment preserves the mid-flexion trochlear line orientation in total knee arthroplasty: A prospective analysis from the FP-UCBM Knee Study Group.

Stefano Campi, Giancarlo Giurazza, Edoardo Franceschetti, Marco Edoardo Cardinale, Andrea Tanzilli, Pietro Gregori, Michele Paciotti, Biagio Zampogna, Umile Giuseppe Longo, Rocco Papalia

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stefano CampiFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Giancarlo GiurazzaFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.ORCID https://orcid.org/0000-0003-4385-6813
Edoardo FranceschettiFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Marco Edoardo CardinaleFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Andrea TanzilliFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Pietro GregoriFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Michele PaciottiFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Biagio ZampognaFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Umile Giuseppe LongoFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Rocco PapaliaFondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeKinematic alignment (KA) in total knee arthroplasty (TKA) aims to restore the patient's native joint anatomy by resurfacing the distal and posterior femoral condyles. However, the trochlear anatomy is often overlooked, raising concerns about potential relative internal rotation of the femoral component. The aim of this study was to define the 𠄈mid-flexion trochlear line' (MTL) and assess its orientation relative to the posterior condylar line, hypothesising a parallelism between the two.

methodsA total of 158 knees (145 patients) undergoing KA TKA were prospectively analysed, after excluding post-traumatic osteoarthritis, cases with trochlear dysplasia, and femoral component flexion >5°. The anterior chamfer cut was conducted with a posterior referencing guide and the most prominent points of the medial and lateral trochlear facets-defining the MTL-were measured with a caliper. The MTL orientation relative to the posterior condylar line was calculated as the difference between the medial and lateral trochlear facets, with the two lines considered parallel for differences of 0 ± 1 mm. Two one-sided tests was implemented to assess equivalence between the two lines within a ±1 mm threshold. Correlations with coronal plane parameters (hip-knee-ankle angle [HKA], medial proximal tibial angle [MPTA] and lateral distal femoral angle [LDFA]) were assessed with Pearson's correlation coefficient. Statistical significance was set at p < 0.05.

resultsThe mean difference between the medial and lateral trochlear facets was 0.1 ± 1.40 mm, with 81.7% of cases falling within the 0 ± 1 mm range, indicating parallelism between the posterior condylar line and the mid-flexion trochlear line (p  =  0.709). No significant correlations were observed between MTL orientation and HKA, MPTA or LDFA.

conclusionsReferencing the posterior condylar line accurately restores MTL orientation in the vast majority of patients, irrespective of coronal plane parameters. These findings support the biomechanical rationale of kinematic alignment, dispelling concerns about femoral component internal rotation. LEVEL OF EVIDENCE: Level IV, prospective observational study.

Indexed as

Arthroplasty, Replacement, KneeFemurKnee JointOsteoarthritis, KneeRange of Motion, ArticularAgedAged, 80 and overBiomechanical PhenomenaFemaleHumansMaleMiddle AgedProspective Studieskinematic alignment (KA)mid‐flexion trochlear line (MTL)total knee Arthroplasty (TKA)trochlear restoration

Identifiers

PMID40827491
PMCPMC12948343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.