SynthesisEpilepsia2025
Peri-ictal imaging abnormalities in non-convulsive status epilepticus: A systematic review and meta-analysis comparing magnetic resonance imaging and computed tomography perfusion.
Synthesis in Epilepsia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Crossed cerebellar diaschisis in status epilepticus: A systematic review of the literature.Epileptic disorders : international epilepsy journal with videotape · 2026Pooled it
- Pooled it
- Assessing cognitive impairment in epilepsy using Arterial spin-labeled (ASL) perfusion imaging.Brain imaging and behavior · 2026Article
- Neuroimaging of the ictal-interictal continuum: Where do we stand? A systematic review and meta-analysis of current evidence.Epilepsia open · 2026Review
- Review
- CT perfusion abnormalities in status epilepticus: associations with clinical characteristics, EEG, and outcome measures.Journal of neurology · 2026Article
- Response: An etiology-driven framework for status epilepticus and ictal-interictal continuum.Epilepsia · 2026Article
- Ictal-interictal continuum and status epilepticus: Two sides of the same coin? A prospective magnetic resonance imaging study.Epilepsia · 2026Article
- Peri-Ictal MRI Abnormalities and Risk of Unprovoked Seizures After De Novo Status Epilepticus.Neurology · 2026Article
- Brain perfusion imaging in patients with status epilepticus, seizures, and IIC patterns.Clinical neurophysiology practice · 2026Review
- Peri-ictal Hyperperfusion Revealed by Arterial Spin Labeling Perfusion Images in 2 Patients with Post-aneurysmal Subarachnoid Hemorrhage Epilepsy and Associated Old Infarction in the Middle Cerebral Artery Territory.NMC case report journal · 2026Article
- Reconsidering non-convulsive status epilepticus diagnosis: 2.5 Hz or etiology-driven frequency cutoffs?Epilepsia · 2026Article
- Pharmacological strategies for preventing post-stroke seizures and epilepsy.Frontiers in neurology · 2025Review
- Rethinking the electrographical boundaries of status epilepticus: controversies and paradoxes of the ictal-interictal continuum.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess and compare the detection rates of peri-ictal abnormalities using magnetic resonance imaging (MRI) and computed tomography perfusion (CTP) in patients with non-convulsive status epilepticus (NCSE).
methodsWe conducted a systematic literature search in five databases up to February 2025. Studies reporting peri-ictal MRI abnormalities (PMAs) or cerebral perfusion abnormalities (CPAs) in patients with NCSE were included. Meta-analyses of proportions were performed using a random-effects model. Subgroup analyses and meta-regression were used to compare detection rates across imaging modalities.
resultsNineteen studies were included (15 MRI, 4 CTP), comprising 562 patients for MRI and 72 for CTP. The pooled detection rate of peri-ictal abnormalities was 50.0% (95% confidence interval [CI]: 34.0%-65.0%) for MRI and 79.3% (95% CI: 54.3%-92.5%) for CTP. Among the MRI modalities, arterial spin labeling (ASL) demonstrated the highest detection rate at 88.8% (95% CI: 32.9%-99.2%). CTP showed a significantly higher detection rate than MRI (χ
conclusionsCTP demonstrates a higher detection rate than conventional MRI for peri-ictal abnormalities in patients with NCSE, supporting its utility in rapid diagnosis and differential workup. Among MRI sequences, ASL showed the highest detection rates, highlighting its potential role in the diagnostic assessment of NCSE. Although MRI remains essential for clarifying etiology, its effectiveness in detecting PMA is highly dependent on the sequences used.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.