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Prognostic value of red cell distribution width-to-albumin ratio in septic patients with malignancies: A retrospective cohort study based on the MIMIC-IV database.
Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association of red blood cell distribution width to albumin ratio with all-cause and cardiovascular mortality among adults with MASLD.BMC gastroenterology · 2026Article
- The red cell distribution width to albumin ratio as a novel biomarker for predicting short-term mortality in severe pulmonary sepsis: a retrospective study with dual-cohort validation.Frontiers in medicine · 2026Article
- Hematologic and metabolic indices for predicting 28-day mortality in sepsis patients: a retrospective intensive care cohort study.Frontiers in medicine · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectiveTo investigate the prognostic value of red cell distribution width-to-albumin ratio (RAR) in sepsis patients with malignancies and evaluate its association with in-hospital mortality.MethodsThe retrospective cohort study was conducted using data extracted from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Participants were stratified into quartiles (Q1-Q4) based on RAR levels measured within 24 hours of intensive care unit admission. The primary outcome was 28-day in-hospital all-cause mortality. Associations between RAR and clinical outcomes were assessed using Kaplan-Meier survival analysis, multivariate Cox proportional hazards regression and restricted cubic spline (RCS) modeling. Predictive performance was further evaluated through receiver operating characteristic (ROC) analysis and decision curve analysis (DCA).ResultsA total of 1686 eligible patients were included. Multivariate Cox regression revealed a significant positive association between RAR and 28-day in-hospital mortality (adjusted model 3 HR = 1.12, 95% CI: 1.08-1.16,
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