Evidence map›Paper›PMID 40827282›Full record

ArticleInternational journal of ophthalmology2025

Ocular biological characteristics of children with myopia and rapid axial length changes treated with spectacles with highly aspherical lenslets.

Jing Zhai, Hao Chen, Xin-Jie Ye, Wei-Jun Cai, Li-Jie Hou, Mei-Xiao Shen, Fan Lyu

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Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jing ZhaiNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Hao ChenNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Xin-Jie YeNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Wei-Jun CaiNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Li-Jie HouNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Mei-Xiao ShenNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Fan LyuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the ocular biological characteristics of children with myopia and rapid axial length (AL) changes prescribed spectacles with highly aspherical lenslets (HAL).

methodsData were collected from 156 children (252 eyes) with myopia and HAL treatment who were aged 7-13 and had rapid AL changes. The participants were divided into groups with AL reduction and elongation according to the changes in AL within 6mo. Paired

resultsThe ocular biological parameters significantly changed in the children with myopia and rapid AL changes after HAL treatment. In the group with AL reduction, the anterior chamber depth (ACD) and vitreous chamber depth (VCD) decreased. The crystalline lens thickness (CLT) increased, corneal flat keratometry (FK) decreased, and steep keratometry (SK) increased (all

conclusionIn the eyes with HAL treatment, decreased ACD and VCD, thickened CLT, flattened FK, and steepened SK are observed during AL reduction. Lower baseline astigmatism is associated with AL reduction. The AL reduction may suggest the potential efficacy of HAL intervention in myopia control, while providing evidence for optimizing personalized myopia management strategies. Further longitudinal studies are warranted to validate whether rapid AL changes predict sustained treatment efficacy.

Indexed as

astigmatismaxial lengthhighly aspherical lensletsmyopia

Identifiers

PMID40827282
PMCPMC12311456

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