Evidence map›Paper›PMID 40827255›Full record

ArticleJournal of neuroendovascular therapy2025

Effect of Left Ventricular Systolic Dysfunction on the Outcome of Mechanical Thrombectomy.

Satoshi Miyamoto, Yoshiro Ito, Shinichiro Numao, Shun Tanaka, Takato Hiramine, Toshihide Takahashi, Sho Okune, Hisayuki Hosoo, Mikito Hayakawa, Aiki Marushima and 3 more

Abstract read
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In one paragraph

Article in Journal of neuroendovascular therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Satoshi MiyamotoDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Yoshiro ItoDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Shinichiro NumaoDepartment of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.
Shun TanakaDepartment of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.
Takato HiramineDepartment of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.
Toshihide TakahashiDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Sho OkuneDepartment of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.
Hisayuki HosooDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Mikito HayakawaDepartment of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.
Aiki MarushimaDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Hiroshi YamagamiDepartment of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.
Eiichi IshikawaDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Yuji MatsumaruDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Left ventricular systolic dysfunction has traditionally been considered an unfavorable prognostic factor in stroke. However, chronic hypoperfusion due to this dysfunction may improve cerebral collateral flow, potentially serving as a compensatory mechanism during ischemic stroke. This study aimed to investigate the effects of left ventricular systolic dysfunction on outcomes after mechanical thrombectomy (MT), with a focus on cerebral collateral flow. Methods: This retrospective cohort study included 94 consecutive patients with acute ischemic stroke who underwent MT between April 2017 and July 2022. Patients were divided into 2 groups based on their left ventricular ejection fraction (EF): the reduced EF group (EF ≤40%) and the preserved EF group (EF >40%). We evaluated post-treatment stroke volume, clinical outcomes, length of hospital stay, and the relationship between EF and cerebral collateral flow. Results: The reduced and preserved EF groups consisted of 11 (12%) and 83 (88%) patients, respectively. No significant differences were observed in post-treatment stroke volume (13 vs. 12 cm Conclusion: Left ventricular systolic dysfunction did not significantly worsen outcomes after MT. Chronic cerebral hypoperfusion due to left ventricular systolic dysfunction may promote the development of cerebral collaterals, potentially enhancing resistance to ischemic events.

Indexed as

cerebral collateral flowheart failureischemic strokemechanical thrombectomyreduced ejection fraction

Identifiers

PMID40827255
PMCPMC12358220

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.