ArticleJournal of the American Heart Association2025
Effects of Alcohol Septal Ablation on Exercise Hemodynamics, Symptoms, and Quality of Life in Obstructive Hypertrophic Cardiomyopathy.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A case report of ventricular suicide following transcatheter aortic valve replacement for severe aortic stenosis in a patient with hypertrophic cardiomyopathy: the danger of abrupt afterload reduction.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of alcohol septal ablation (ASA) on exercise hemodynamics, symptoms, and quality of life in patients with obstructive hypertrophic cardiomyopathy is poorly described according to contemporary standards. This study aimed to evaluate the effect of ASA on filling pressures at rest and during exercise, left ventricular outflow tract obstruction, symptoms, and quality of life in patients with obstructive hypertrophic cardiomyopathy.
methodsThis prospective study enrolled 24 patients with obstructive hypertrophic cardiomyopathy referred for ASA. Right-heart catheterization and echocardiography were performed at rest and during exercise, before and ≈7 months after ASA. The primary outcome was the difference in pulmonary artery wedge pressure at 75 W. Secondary outcomes assessed left ventricular outflow tract gradients, New York Heart Association functional class, and the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score.
resultsASA significantly reduced pulmonary artery wedge pressure at 75 W (33±9 mm Hg versus 24±10 mm Hg;
conclusionsASA significantly reduced exercise-induced filling pressures and LVOT obstruction, leading to improved symptoms and quality of life in patients with obstructive hypertrophic cardiomyopathy.
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