Evidence map›Paper›PMID 40826480›Full record

ArticleJournal of health, population, and nutrition2025

Burden of opioid use disorder in the Middle East and North Africa (MENA): findings from Global Burden of Disease (GBD) study.

Mohammad Effatpanah, Homa Seyedmirzaei, Hossein Karami, Pegah Rasoulian, Reza Mehrizi, Khashayar Danandeh, Leila Ghamkhar, Zeynab Efatpanah, Amin Nakhostin-Ansari

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Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mohammad EffatpanahPediatric Department, School of Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Homa SeyedmirzaeiOccupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Hossein KaramiNational Center for Health Insurance Research, Tehran, Iran.
Pegah RasoulianNeuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Reza MehriziNational Center for Health Insurance Research, Tehran, Iran.
Khashayar DanandehNeuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Leila GhamkharNational Center for Health Insurance Research, Tehran, Iran.
Zeynab EfatpanahSchool of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Amin Nakhostin-AnsariNeuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Iran. a-nansari@alumnus.tums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOpioid Use Disorders (OUDs) present critical health challenges across the Middle East and North Africa (MENA) region. The primary objective of this study is to assess the prevalence and burden of OUDs within the MENA region.

methodsIn the current study, we used the Global Burden of Diseases (GBD) 2019 study data. In the GBD study, OUDs were defined as the ICD-10 codes of F11.0-F11.9, P96.1, and R78.1 and the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) code of 304.00. We retrieved the prevalence, death, and disability-adjusted life year (DALY) crude rates and age-standardized rates for OUDs throughout MENA countries, the MENA area, and globally, across years (from 1990 to 2019), genders, and age groups.

resultsAge-standardized DALY rate of OUDs in MENA increased by 40.6%, from 104.4 (95% UI: 78.2-136.0) in 1990 to 147.0 (95% UI: 111.8-187.7) per 100,000 people in 2019. In 2019, the highest DALY rate of OUDs for both males (411.3 per 100000) and females (330.2 per 100000) and in total (372.3 per 100000) was in the 25-29 years age group. In 2019, the highest age-standardized DALY rates of OUDs were UAE (373.9 per 100000, 95% UI: 278.2-481.7), Libya (341.1 per 100000, 95% UI: 248.9-435.8), and Iran (281.5 per 100000, 95% UI: 221.1-349.0). Age-standardized DALY rates decreased in Qatar (-10.2%) and Iraq (-1.9%) from 1990 to 2019. While, age-standardized DALY rates increased in other countries, with the highest increases being in Libya (167.3%), Lebanon (121.1%), and UAE (113.31%).

conclusionsThe burden of OUDs has increased from 1990 to 2019 in the MENA region. These results necessitate new governmental policies and global collaborations to effectively control opioid production and trafficking and manage their negative health-related outcomes.

Indexed as

Global Burden of DiseaseOpioid-Related DisordersAdolescentAdultAfrica, NorthernAgedChildCost of IllnessDisability-Adjusted Life YearsFemaleHumansMaleMiddle AgedMiddle EastPrevalenceYoung AdultBurdenEpidemiologyMiddle eastNorth africaOpioid use disorders

Identifiers

PMID40826480
PMCPMC12363103

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.