Evidence map›Paper›PMID 40826431›Full record

ReviewEuropean journal of medical research2025

SOX9: an important factor in regulating breast cancer.

Yaru Wang, Juhang Chu, Luyao Huang, Mingping Qian

Abstract readReview
In one paragraph

Review in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Role of SOX9 protein in ovarian carcinoma: A molecular insight.The Indian journal of medical research · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yaru WangShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.
Juhang ChuShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.
Luyao HuangShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.
Mingping QianShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China. qian_mp1@126.com.

Funding

Shanghai Hospital Development Center Foundation SHDC2022CRS033Shanghai Municipal Health Commission Research Project 2020HP11
6 · The paper itself

Abstract

The SRY-Box Transcription Factor 9 (SOX9) is a crucial transcription factor that controls the growth, differentiation, and stemness of progenitor cells. According to research, SOX9 protein controls the initiation and progression of tumors by directly participating in tumor initiation, proliferation, migration, and chemotherapy resistance. Although SOX9 overexpression is frequently found in breast cancer, the precise molecular mechanism is yet unknown. This article reviews the structure, function, and new developments of SOX9 in the pathogenesis and treatment of breast cancer, and proposes that targeting SOX9 may improve the therapeutic effect of breast cancer and provide a reference for clinical work.

Indexed as

Breast NeoplasmsSOX9 Transcription FactorAnimalsCell ProliferationDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticHumansSOX9 protein, humanSOX9 Transcription FactorBreast cancerDevelopmentOccurrenceSOX9Treatment

Identifiers

PMID40826431
PMCPMC12360010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.