ArticleBMC geriatrics2025
Association between prognostic nutritional index and risk of moderate-to-severe basic activities of daily living dependence two years after hip fracture surgery in older adults.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of multidimensional biomarkers of immune, nutritional, inflammatory, and metabolic status with postoperative outcomes in older hip fracture patients: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Preoperative neutrophil-to-lymphocyte ratio and refracture risk in hip fracture patients: a propensity score-matched analysis.Annals of medicine · 2026Article
- Association between preoperative prognostic nutritional index and postoperative delirium in older adults with hip fractures: a real-world study.Annals of medicine · 2026Article
- Early oral nutritional supplementation and postoperative recovery after hip arthroplasty in malnourished older adults with femoral neck fracture.Frontiers in nutrition · 2026Article
- Composite inflammatory biomarkers for predicting vascular crisis after finger replantation: a two-center retrospective study identifying a promising inflammatory biomarker and its multidimensional evaluation.Frontiers in immunology · 2026Article
- Nutrition-related clinical laboratory indicators in perioperative management of geriatric hip fractures: a narrative review from risk stratification to precision intervention.Frontiers in nutrition · 2026Review
- Association of lipid accumulation product with the prevalence and incidence of sarcopenia: a nationwide study in Chinese.Nutrition & metabolism · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundHip fractures are a common and serious health concern in older adults. The ability to perform basic activities of daily living (BADL) is a key indicator of long-term functional status. This study aimed to evaluate the prognostic value of the Prognostic Nutritional Index (PNI) in identifying older patients at risk of moderate-to-severe BADL dependence two years after hip fracture surgery.
methodsA total of 526 older patients with hip fractures were included in the analysis. Baseline characteristics and preoperative indicators were systematically examined. Univariate and multivariate logistic regression models were applied to identify independent factors associated with moderate-to-severe BADL dependence. Restricted cubic spline (RCS) analysis was used to explore potential nonlinear relationships, while receiver operating characteristic (ROC) curves evaluated the discriminatory performance of PNI. Subgroup analysis was performed to explore population differences. Propensity score matching (PSM) was performed to enhance robustness and control for confounding factors.
resultsThe median age of the cohort was 73.0 years (interquartile range: 67.0-79.0), and 69.96% of participants were female. A total of 43 patients (8.17%) exhibited moderate-to-severe BADL dependence at two years postoperatively. Multivariate logistic regression revealed that higher preoperative PNI was independently associated with a lower risk of long-term dependence (OR: 0.90; 95% CI:0.82-0.99; P = 0.026). ROC analysis demonstrated a moderate discriminatory ability (AUC = 0.659), and RCS analysis indicated a linear relationship between PNI and BADL dependence (P-nonlinearity = 0.674). The association remained robust after PSM.
conclusionPreoperative PNI is an independent predictor of long-term functional dependence in older patients undergoing hip fracture surgery. These findings underscore the importance of nutritional assessment and optimization in preoperative care to improve postoperative functional outcomes in this vulnerable population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.