Evidence map›Paper›PMID 40826345›Full record

SynthesisBMC musculoskeletal disorders2025

Intramedullary nailing with and without cerclage in subtrochanteric fractures: an updated systematic review and meta-analysis.

Ahmed Oun, Omar Abdelaziz, Islam Saeed Elhois, Mohamed Al-Badaineh, Karim Zinhom, George Jabrieh, Hamza S Al-Himyari, Abdullah A Nada

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmed OunFaculty of Medicine, Tanta University Hospital, Tanta University, Tanta, Egypt. ahmed_30942176@med.tanta.edu.eg.ORCID http://orcid.org/0009-0007-9686-7758
Omar AbdelazizFaculty of Medicine, Alexandria University, Alexandria, Egypt.
Islam Saeed ElhoisDepartment of orthopedics, Qena General Hospital, Ministry of health and population, Qena, Egypt.
Mohamed Al-BadainehJordan University of science and Technology, Irbid, Jordan.
Karim ZinhomFaculty of medicine, October 6 University, Giza, Egypt.
George JabriehFaculty of medicine and Health sciences, Palestine Polytechnic University, Hebron, Palestine.
Hamza S Al-HimyariDepartment of orthopedics, Mabara Elmaadi Hospital, Ministry of health and population, Cairo, Egypt.
Abdullah A NadaFaculty of Medicine, Tanta University Hospital, Tanta University, Tanta, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntramedullary nailing (IMN) is the gold standard for femoral subtrochanteric fractures (FSF) treatment due to their biomechanical advantages and minimally invasive nature. However, achieving proper reduction remains challenging in unstable patterns, leading to poor outcomes. Cerclage wiring, used alongside IMN, has shown potential in improving fracture stability and alignment, yet concerns regarding soft tissue damage persist. This systematic review and meta-analysis aims to evaluate the impact of cerclage wiring on clinical and radiological outcomes in FSF treatment.

methodsA comprehensive literature search was conducted for studies published up to the 3rd of March 2025 using PubMed, Scopus, Google Scholar, and Web of Science databases, focusing on randomized controlled trials and observational studies comparing intramedullary nailing with and without cerclage wiring in subtrochanteric fractures fixation. Eleven eligible studies, encompassing 658 patients, were included. The risk of bias was assessed using the Newcastle–Ottawa scale and meta-analytical techniques were employed to calculate pooled effect sizes and statistical significance.

resultsEleven retrospective studies were included revealing that cerclage wiring significantly increased operative time; p > 0.001, blood loss; p = 0.031, and better functional outcomes as union time significantly decreased; p = 0.026, significantly better Harris Hip Score; p = 0.012, while improving reduction quality. No significant differences were observed in non-union, infection, or mortality rates. Quality assessment using the Newcastle–Ottawa Scale indicated high quality studies.

conclusionCerclage wiring in conjunction with intramedullary nailing (IMN) for subtrochanteric fractures provides considerable advantages in our study in terms of the quality of fracture reduction, healing duration, and functional rehabilitation, especially in more complicated cases, even though it may lead to longer surgical times and greater blood loss.

Indexed as

Bone WiresFracture Fixation, IntramedullaryHip FracturesBone NailsHumansOperative TimeProximal Femoral FracturesTreatment OutcomeCerclageFemurIntramedullary nailSubtrochanteric fractures

Identifiers

PMID40826345
PMCPMC12359860

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.