ArticleBMC cardiovascular disorders2025
Association of prognostic nutritional index and severe abdominal aortic calcification in middle-aged adults: a cross-sectional study.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Preoperative nutritional status and its association with adverse events following open abdominal aortic aneurysm repair.Frontiers in nutrition · 2026Article
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4 authors.
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Abstract
backgroundThe prognostic nutritional index (PNI) serves as an indicator of systemic inflammation, immunological function, and nutritional condition in individuals. The aim of this study was to investigate the potential association between PNI and severe abdominal aortic calcification (SAAC) in middle-aged adults.
methodsThe study included 1,436 subjects aged 40-60 years (average age 49.72 years, with females representing 50.97%) from the 2013-2014 NHANES. AAC scores greater than 6 is defined as SAAC. PNI was defined as 5× Lymphocyte Count (10
resultsIn fully adjusted models, each unit increase in PNI was also associated with a 11% increase in the risk of SAAC occurrence [OR (95% CI): 1.11 (1.07, 1.16)]. Subgroup analyses showed that the relationship between PNI and SAAC was modified by hypertension (P-interaction < 0.0001). In the nonhypertensive population, the association between PNI and SAAC was significantly positive.
conclusionsWe found that nutritional status combined with inflammation did not have a protective effect on SAAC. Conversely, in middle-aged individuals (especially those without hypertension), higher PNI scores were associated with a higher risk of SAAC, which was unexpected.
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