SynthesisLasers in medical science2025
Comparative efficacy and safety of low-level laser therapy and topical Minoxidil combination vs. topical Minoxidil monotherapy in androgenetic alopecia management: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Topical minoxidil is currently a standard treatment for androgenic alopecia (AGA). Low-level laser therapy (LLLT) is an innovative technology that may enhance the hair growth effects of minoxidil. This study intends to evaluate the efficacy and safety of the combination therapy of LLLT and topical minoxidil in comparison to topical minoxidil alone for the treatment of AGA. A thorough search was performed on the Cochrane Library, ClinicalTrials.gov, Europe PMC, Medline, and Scopus databases until March 25th, 2025. All randomized controlled trials (RCTs) that examined the comparison between LLLT combined with topical minoxidil and topical minoxidil alone for AGA were included in this review. We utilized random-effects models to evaluate the risk ratio (RR) and mean difference (MD) for the outcomes presented. A total of 7 RCTs were incorporated. The findings of our meta-analysis indicated that the combination of LLLT and topical minoxidil was correlated with a greater increase in hair density (MD 6.62; 95%CI: 2.04, 11.20, p = 0.005, I
Indexed as
Identifiers
40826200What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.