ArticleInternational journal of colorectal disease2025
Long-term outcomes of transanal irrigation in patients with low anterior resection syndrome: what happens after more than five years?
Article in International journal of colorectal disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- [Anorectal functional disorders following organ-preserving treatment and resection of rectal cancer].Chirurgie (Heidelberg, Germany) · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow anterior resection syndrome (LARS) significantly impacts quality of life after rectal cancer surgery. Transanal irrigation (TAI) is a potential treatment, but long-term outcome data are limited. This study aims to evaluate the efficacy and safety of TAI in LARS patients after more than 5 years of follow-up.
methodsFrom April 2015 to December 2019, consecutive patients with LARS following low anterior resection for rectal cancer, trained in TAI at Careggi University Hospital, were prospectively collected. Patients with LARS scores > 30 or those failing conservative management were included. TAI was performed using the Peristeen® device, with a standard protocol of 400-600 ml irrigation 3-4 times/week. Primary outcomes were maintenance of TAI benefits and patient satisfaction (VAS).
resultsAfter an appropriate training and evaluation period, 35 patients were referred to TAI. While interruptions in the first year were mainly related to technical problems, ineffectiveness, or the onset of other clinical problems, afterward, patients tended to discontinue treatment only in the event of death (6 patients) or clinical well-being (5 patients). At the last follow-up control, with a median follow-up of 89 months, 15 patients (43%) still used TAI treatment. The median VAS satisfaction score for bowel control was 8.2.
conclusionsTAI demonstrates sustained benefits in LARS patients over 5 years, with significant symptom improvement and high patient satisfaction. Further studies are needed to identify predictors of long-term success.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.