ArticleJournal of translational medicine2025
Retinal vasculature in indirect traumatic optic neuropathy with endoscopic optic canal decompression.
Article in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Baseline retinal nerve fiber layer thickness as a predictive biomarker for endoscopic optic canal decompression in NAION: towards a precision medicine approach.Journal of translational medicine · 2026Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTo quantify alteration of retinal peripapillary microvasculature and visual function within three months follow-up in indirect traumatic optic neuropathy (ITON) after endoscopic trans-ethmosphenoid optic canal decompression (ETOCD). METHODOLOGY: Thirty-seven ITON eyes were included. Radial peripapillary capillary (RPC) density at pre-operation and post-operation within three months follow-up (pre-op, post-op 2 weeks, post-op 1 month and post-op 3 months) was analyzed. The comparisons of RPC density and best corrected visual acuity (BCVA) at different points were analyzed.
resultsIn ITON eyes, preoperative global RPC density was reduced compared to unaffected eyes (P ≤ 0.001). Global RPC density of ITON at pre-op, post-op 2 weeks, 1 month and 3 months were 47.71 ± 7.36, 40.56 ± 8.71, 40.75 ± 7.06 and 33.95 ± 8.03, respectively. For ITON eyes, three points' post-op global RPC density significantly differed from pre-op RPC density (All P ≤ 0.006). BCVA of ITON at pre-op, post-op 2 weeks, 1 month and 3 months were 2.41 ± 1.61, 1.84 ± 1.43, 1.54 ± 1.39 and 1.54 ± 1.38, respectively. A significant difference had been found at post-op 1 month and post-op 3 months when compared to pre-op BCVA (P = 0.018 and 0.015, respectively).
conclusionsThe reduced RPC density occurred in ITON with a plateau between post-op 2 weeks and post-op 1 month. The visual improvement might be secondary to the alteration of retinal perfusion after ETOCD for a long time, though discrepancies in structural-functional resilience existed.
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