Evidence map›Paper›PMID 40826095›Full record

ReviewCritical care (London, England)2025

Neuroimaging for neurovascular complications of traumatic brain injury.

Laura Saitta, Martina Resaz, Chiara Robba, Giacomo Rebella, Claudia Rolla Bigliani, Giancarlo Salsano, Bruno Del Sette, Nicola Mavilio, Francesco Pasetti, Nicolò Patroniti and 2 more

Abstract readReview
In one paragraph

Review in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laura Saitta *U.O. Neuroradiologia, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Martina Resaz *U.O. Neuroradiologia, Istituto Giannina Gaslini IRCCS, Genoa, Italy. martinaresaz@gaslini.org.
Chiara RobbaIntensive Care Unit, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Giacomo RebellaU.O. Neuroradiologia, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Claudia Rolla BiglianiU.O. Neuroradiologia, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Giancarlo SalsanoU.O. Neuroradiologia, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Bruno Del SetteU.O. Neuroradiologia, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Nicola MavilioU.O. Neuroradiologia, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Francesco PasettiU.O. Radiologia, Istituto Giannina Gaslini IRCCS, Genoa, Italy.
Nicolò PatronitiIntensive Care Unit, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Lucio Castellan *U.O. Neuroradiologia, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Luca Roccatagliata *U.O. Neuroradiologia, Ospedale Policlinico San Martino, IRCCS for Oncology and Neuroscience, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraumatic brain injury typically causes extra-axial and/or intra-axial bleeding including subarachnoid hemorrhage, intraparenchymal hemorrhage, subdural hematomas and epidural hematomas. Less commonly, trauma can cause cerebrovascular complications, which involve either the arterial or the venous side. Because of the rarity of these pathological conditions, guidelines and recommendations for their management are still controversial. MAIN BODY: The objective of this work is to describe the possible cerebrovascular complications of critically ill traumatic brain injured patients and to understand the most common underlying mechanisms and radiological features as well as their management. A variety of pathological entities will be addressed, such as post-traumatic aneurysms, carotid-cavernous fistula, arterial occlusion, arterial dissection (in potential association with brain ischemia), as well as arterial rupture/avulsion and post-traumatic venous thrombosis. Neurovascular complications of head trauma vary depending on the traumatic mechanism, on the site of impact and on the osseous structures involved. Early diagnosis is mostly based on Computed Tomography/Computed Tomography Angiography (CT/CTA) whose findings help guide patient management by detecting vascular lesions potentially leading to neurological deterioration. Magnetic resonance imaging may be useful in selected cases. Today Digital Subtraction Angiography (DSA) is mostly a diagnostic problem-solving tool when CTA findings are equivocal but advanced endovascular interventional techniques have improved the therapeutic possibilities in post-traumatic vascular complications. 

conclusionsNeurovascular complications are not common after head trauma but should not be overlooked because they might lead to severe and life-threatening consequences. Early diagnosis, and a multidisciplinary collaboration including neuroradiologists, neurosurgeons and neurointensivists is fundamental in order to prevent and minimize secondary brain damage in this population.

Indexed as

Brain Injuries, TraumaticCerebrovascular DisordersNeuroimagingHumansMagnetic Resonance ImagingTomography, X-Ray ComputedNeurocritical careNeuroimagingNeurovascular complicationsTraumatic brain injury

Identifiers

PMID40826095
PMCPMC12362949

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.