Evidence map›Paper›PMID 40826092›Full record

ArticleBMC health services research2025

Stem cell transplantation cost in Iran.

Fereshte Karimi, Ali Mohammad Mosadeghrad, Mohammad Vaezi, Ghasem Janbabaei, Hoda Ghobeishipour, Mohammad Hussein Nozarian, Seyed Asadollah Mousavi, Hossein Kamranzadeh Fumani, Soroush Rad, Maryam Barkhordar and 3 more

Abstract read
In one paragraph

Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fereshte Karimi *Research Center for Emergency and Disaster Resilience, Red Crescent Society of the Islamic Republic of Iran, Tehran, Iran.
Ali Mohammad Mosadeghrad *Department of Health Management, Policy and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad VaeziHematology, Oncology and Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
Ghasem JanbabaeiHematologic Malignancies Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
Hoda GhobeishipourDepartment of Health Management, Policy and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Hussein NozarianDepartment of Health Management, Policy and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Asadollah MousaviCell Therapy and Hematopoietic Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
Hossein Kamranzadeh FumaniHematology, Oncology and Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
Soroush RadHematology, Oncology and Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
Maryam BarkhordarCell Therapy and Hematopoietic Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
Sahar Tavakoli ShirajiHematologic Malignancies Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
Ardeshir GhavamzadehCancer and Cell Therapy Research Center, Tehran University of Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
Marjan YaghmaieHematology, Oncology and Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran. marjix58@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStem cell transplantation (SCT) is a crucial treatment for various blood disorders and cancers. This procedure involves the transfer of healthy stem cells to replace damaged or diseased cells, restoring healthy blood cell production and alleviating symptoms. This study aimed to calculate the total cost of SCT at Shariati Hospital, Tehran, Iran.

methodA retrospective cross-sectional design was employed, analyzing data from 143 SCT patients admitted between August 2022 and March 2023. Activity-Based Costing (ABC) was utilized to allocate costs across combined operational centers, encompassing intermediate clinical support and patient care units. Cost data were extracted from hospital financial records and analyzed using SPSS and Excel in 2024.

resultsPatients had a mean age of 39 years and an average hospital stay of 27.2 days. The mean total cost per patient was 2,166,904,089 IRR (approximately $51,594 USD), equivalent to 24,232 international dollars based on Purchasing Power Parity (PPP) adjustment. Direct medical costs constituted 49% of total expenses, with overhead costs comprising 51%. Human resources accounted for the largest cost components, notably physicians (38.8%) and nursing staff (13.8%). Government subsidies covered 54.1% of direct costs, followed by out-of-pocket payments (13.9%) and basic insurance (12.8%).

conclusionStem cell transplantation imposes a substantial financial burden on the healthcare system in Iran. These findings underscore the urgent need for policy interventions to optimize resource allocation, establish standardized tariffs, and implement mechanisms that improve access and provide financial protection for patients.

Indexed as

Stem Cell TransplantationAdolescentAdultCross-Sectional StudiesFemaleHumansIranMaleMiddle AgedRetrospective StudiesYoung AdultActivity based costingCost analysisIranStem cell transplant

Identifiers

PMID40826092
PMCPMC12360016

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.