Evidence map›Paper›PMID 40826091›Full record

ReviewVirology journal2025

Participation of host cell proteins in inclusion bodies of non-segmented RNA virus infected cells: a molecular insight.

Sharmistha Sarkar, Kriti Kestur Biligiri, Nisha Vats, Shravanti Rampalli, Surajit Ganguly, Naveen Kumar, Debi Prasad Sarkar, Nirmal Kumar Ganguly, Nishi Raj Sharma

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sharmistha SarkarSchool of Interdisciplinary Sciences and Technology, Department of Molecular Medicine, Jamia Hamdard, Hamdard Nagar, New Delhi, 110062, India.
Kriti Kestur BiligiriCouncil of Scientific and Industrial Research (CSIR), Institute of Genomics and Integrative Biology (IGIB), New Delhi, 110025, India.
Nisha VatsDepartment of Education and Research (AERF), Artemis Hospitals, Gurugram, 122001, Haryana, India.
Shravanti RampalliCouncil of Scientific and Industrial Research (CSIR), Institute of Genomics and Integrative Biology (IGIB), New Delhi, 110025, India.
Surajit GangulySchool of Interdisciplinary Sciences and Technology, Department of Molecular Medicine, Jamia Hamdard, Hamdard Nagar, New Delhi, 110062, India.
Naveen KumarIndian Council of Medical Research (ICMR)-National Institute of Virology (NIV), Pune, 411001, Maharashtra, India.
Debi Prasad SarkarDepartment of Biochemistry, University of Delhi South Campus, New Delhi, 110021, India.
Nirmal Kumar GangulyDepartment of Education and Research (AERF), Artemis Hospitals, Gurugram, 122001, Haryana, India.
Nishi Raj SharmaSchool of Interdisciplinary Sciences and Technology, Department of Molecular Medicine, Jamia Hamdard, Hamdard Nagar, New Delhi, 110062, India. raaj13@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Negative-sense RNA viruses (NSVs) carrying a non-segmented genome encompass a broad group of viruses responsible for numerous human diseases such as rabies, mumps, measles, respiratory illness and encephalitis. Viruses replicate intracellular and interact with various host proteins to evade the immune response and persist within the host. A salient trait of NSVs is their ability to form cytoplasmic inclusion bodies (IBs) which are believed to serve as pivotal sites for viral replication. The formation of viral IBs is a complex process involving the recruitment of viral RNA and its proteins along with cellular components. These different constituents of IBs fulfil diverse roles depending on the structure and composition which remains specific to each virus. Therefore, understanding the viral strategies underlying IB formation is imperative. Numerous studies have explored the relationship between virus-induced IBs and host cell factors. This review aims to summarize how cellular factors participate in the formation of distinct viral IBs among non-segmented NSVs.

Indexed as

Host Microbial InteractionsHost-Pathogen InteractionsInclusion BodiesInclusion Bodies, ViralNegative-Sense RNA VirusesAnimalsHumansRNA, ViralVirus ReplicationRNA, ViralDouble-stranded RNAInclusion bodiesIntrinsically disordered regionsLiquid-Liquid phase separationNon-segmented negative sense RNA virusRNA binding domainRNA binding proteinsStress granules

Identifiers

PMID40826091
PMCPMC12362845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.