ArticleNutrition journal2025
Impact of carbohydrate quality on the association between low-carbohydrate diet scores and longitudinal changes of cardiometabolic risk factors.
Article in Nutrition journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Intersection of Precision Nutrition and Bladder Cancer: A Narrative State-of-the-Art Review of Potential Applications and Challenges.Journal of clinical medicine · 2026Review
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Authors and funding
6 authors.
Funding
Abstract
backgroundWhile low-carbohydrate diet (LCD) patterns have been promoted to improve cardiometabolic risk factors, evidence from long-term studies on the impact of carbohydrate quality in these diets remains equivocal. We examined long-term associations among LCD patterns varying in carbohydrate quality and changes in cardiometabolic risk factors.
methodsDietary, health and lifestyle data were collected from Framingham Offspring cohort participants (n = 3294) every 4 years over a median 16.4-year follow-up. We assessed LCD patterns using 2 LCD scores (LCDSs) reflecting higher total fat and protein intake, and lower intake of (i) low-quality carbohydrates (high-quality LCDS, HQ-LCDS) and (ii) high-quality carbohydrates (low-quality LCDS, LQ-LCDS). Adjusted means of annualized changes in cardiometabolic risk factors across quintiles of LCDSs were estimated using repeated measures linear models.
resultsBaseline median age was 55 years, with 54% female participants. Waist circumference annual gains (cm/y) increased across quintiles (mean for Quintile 1, Quintile 5; P-trend) for HQ-LCDS (0.58, 0.69; 0.004), and LQ-LCDS (0.56, 0.74; <0.001). A slower annual increase in systolic blood pressure (mmHg/y) observed for HQ-LCDS (0.16, 0.00; 0.03), and LQ-LCDS (0.21, -0.05; 0.01). Higher HQ-LCDS was associated with a greater annual increase in HDL cholesterol concentrations (mg/dL/y) (0.51, 0.68; 0.005) and greater annual decline in triglyceride concentrations (mg/dL/y) (-1.24, -1.99; <0.001).
conclusionsAlthough both high- and low-quality LCD patterns were associated with greater increases in waist circumference, our findings support recommendations to preserve high-quality carbohydrate in the context of low-carbohydrate diets and to replace low-quality carbohydrate with more healthy energy sources.
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