Evidence map›Paper›PMID 40826044›Full record

ArticleBMC pediatrics2025

Effects of reduced blood pressure dipping on the progression of chronic kidney disease in children.

Li Huarong, Chen Chaoying, Tu Juan, Lin Tiantian, Wang Nannan

Abstract read
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li HuarongDepartment of Nephrology, Capital Center For Children's Health, Capital Medical University, Beijing, 100020, China.
Chen ChaoyingDepartment of Nephrology, Capital Center For Children's Health, Capital Medical University, Beijing, 100020, China. chenchaoying484@126.com.
Tu JuanDepartment of Nephrology, Capital Center For Children's Health, Capital Medical University, Beijing, 100020, China.
Lin TiantianDepartment of Nephrology, Capital Center For Children's Health, Capital Medical University, Beijing, 100020, China.
Wang NannanDepartment of Nephrology, Capital Center For Children's Health, Capital Medical University, Beijing, 100020, China.

Funding

the Beijing Municipal Hospital Research and Cultivation Program Project of China PC2023050
6 · The paper itself

Abstract

backgroundHypertension is a common complication of chronic kidney disease (CKD) in children. It is related to the progression of CKD. However, current guidelines for hypertension management in CKD patients mainly focus on managing patients with above-target blood pressure (BP). The effects of reduced nocturnal BP dipping on CKD progression in children are unclear.

methodsThis single-center, retrospective cohort study analyzed the clinical data of children with stage 2-5 non-dialysis CKD undergoing ambulatory BP monitoring. Clinical characteristics and laboratory parameters of children with and without hypertension and/or reduced nocturnal BP dipping were analyzed.

resultsNinety-four children were included (median age: 10 years; interquartile range [IQR]: 6-12 years; males: 65 [69.1%]). The median estimated glomerular filtration rate (eGFR) was 41 ml/min/1.73 m

conclusionRegardless of whether ambulatory BP was normal, reduced BP dipping was correlated with the risk of renal progression in children with CKD.

Indexed as

Blood PressureCircadian RhythmHypertensionRenal Insufficiency, ChronicBlood Pressure Monitoring, AmbulatoryChildDisease ProgressionFemaleGlomerular Filtration RateHumansMaleProteinuriaRetrospective StudiesAmbulatory blood pressure monitoringBlood pressure dippingChildrenChronic kidney diseaseProgression

Identifiers

PMID40826044
PMCPMC12359907

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.