Evidence map›Paper›PMID 40826015›Full record

ArticleBMC geriatrics2025

Reproducibility and validity of adapted clinical tests for the assessment of muscle strength in community-dwelling older adults living with Alzheimer's disease.

Marcos Paulo Braz de Oliveira, Letícia Bojikian Calixtre, Natália Oiring de Castro Cezar, Carla Lima-Truax, Brendon David Truax, Anielle Cristhine de Medeiros Takahashi, Tatiana de Oliveira Sato, Paulo Henrique Silva Pelicioni, Paula Regina Mendes da Silva Serrão, Larissa Pires de Andrade

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcos Paulo Braz de OliveiraMultidisciplinary Research in Older Adults' Health Laboratory, Physical Therapy Department, Federal University of São Carlos, Washington Luis Highway, Km 235, São Carlos, São Paulo, Brazil. marcospbraz@gmail.com.
Letícia Bojikian CalixtrePhysical Therapy Department, Pernambuco University, Petrolina, Pernambuco, Brazil.
Natália Oiring de Castro CezarMedicine Department, Minas Gerais State University, Passos, Minas Gerais, Brazil.
Carla Lima-TruaxThe University of Alabama at Birmingham, Mechanisms of Spinal Manual Therapy Laboratory, Physical Therapy Department, Birmingham, AL, USA.
Brendon David TruaxThe University of Alabama at Birmingham, Division of Pulmonary, Allergy, and Critical Care, Medicine Department, Birmingham, AL, USA.
Anielle Cristhine de Medeiros TakahashiMultidisciplinary Research in Older Adults' Health Laboratory, Physical Therapy Department, Federal University of São Carlos, Washington Luis Highway, Km 235, São Carlos, São Paulo, Brazil.
Tatiana de Oliveira SatoFederal University of São Carlos, Laboratory of Preventive Physical Therapy and Ergonomics, Physical Therapy Department, São Carlos, São Paulo, Brazil.
Paulo Henrique Silva PelicioniUniversity of New South Wales, Neuroscience Research Australia, School of Health Sciences, New South Wales, Australia.
Paula Regina Mendes da Silva SerrãoFederal University of São Carlos, Rheumatology and Hand Rehabilitation Research Laboratory, Physical Therapy Department, São Carlos, São Paulo, Brazil.
Larissa Pires de AndradeMultidisciplinary Research in Older Adults' Health Laboratory, Physical Therapy Department, Federal University of São Carlos, Washington Luis Highway, Km 235, São Carlos, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlder adults living with Alzheimer's disease (AD) have impaired executive functions and can therefore have greater difficulty following the instructions of assessment tests. Therefore, the objective of this study was to determine the intra- and inter-rater reliability and criterion validity of the adapted Five-Times Sit-to-Stand (5STS), 30-Second Sit-to-Stand (30STS) and Calf-Rise Senior (CRS) tests for the assessment of lower limb muscle strength in older adults living with AD.

methodsA methodological study was conducted. For the adaptation of the 5STS, 30STS and CRS tests, standardized verbal commands were added during the execution to assist the older adults in beginning and ending the tests (5STS and 30STS: "stand up" and "sit down"; CRS: "stand on your tip toes" and "now you can get down"). Reliability was determined using the intraclass correlation coefficient (ICC

resultsForty-two older adults living with AD were included (Mild-AD: 22; Moderate-AD: 20). Intra- and inter-rater reliability were moderate (ICC

conclusionThe adapted 5STS, 30STS and CRS tests demonstrated moderate reliability and correlated with maximum lower limb muscle strength and endurance in older adults living with AD.

Indexed as

Alzheimer DiseaseGeriatric AssessmentIndependent LivingMuscle StrengthAgedAged, 80 and overFemaleHumansMaleReproducibility of ResultsAgedAlzheimer DiseaseDementiaMuscle strengthReproduticibility of results

Identifiers

PMID40826015
PMCPMC12359825

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.