Evidence map›Paper›PMID 40825878›Full record

ReviewCardiovascular toxicology2025

Exploring the Impact of E-cigarettes on Cardiovascular Health: Insights from Preclinical and Clinical Studies.

Tijana Simovic, Chloe L Matheson, Marisa Colon, Caroline O Cobb, Judith Voynow, Youngdeok Kim, Patrick Nana-Sinkam, Ryan Garten, Paula Rodriguez-Miguelez

Abstract readReview
In one paragraph

Review in Cardiovascular toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tijana Simovic *Department of Kinesiology and Health Sciences, Virginia Commonwealth University, 817 West Franklin Street, Richmond, VA, 23284, USA.ORCID 0000-0002-3613-4196
Chloe L Matheson *Department of Kinesiology and Health Sciences, Virginia Commonwealth University, 817 West Franklin Street, Richmond, VA, 23284, USA.ORCID 0009-0006-6460-1237
Marisa ColonDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University, 817 West Franklin Street, Richmond, VA, 23284, USA.
Caroline O CobbDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.ORCID 0000-0003-3258-252X
Judith VoynowDivision of Pediatric Pulmonology, Virginia Commonwealth University, Richmond, VA, USA.ORCID 0000-0002-2437-2859
Youngdeok KimDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University, 817 West Franklin Street, Richmond, VA, 23284, USA.ORCID 0000-0002-6134-0100
Patrick Nana-SinkamDivision of Pulmonary and Critical Care, Virginia Commonwealth University, Richmond, VA, USA.
Ryan GartenDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University, 817 West Franklin Street, Richmond, VA, 23284, USA.ORCID 0000-0002-8939-6093
Paula Rodriguez-MiguelezDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University, 817 West Franklin Street, Richmond, VA, 23284, USA. prodriguezmig@vcu.edu.ORCID 0000-0003-3582-4483

Funding

Project 4: Using a prospective cohort survey to test population-level predictions generated by Projects 1-3U54DA036105 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI FAGAN, PEBBLES · 2018 to 2022
$20.8M
American Heart Association 23PRE1018396Center for Tobacco Products U54DA036105NIDA NIH HHS U54 DA036105
6 · The paper itself

Abstract

Electronic cigarettes are popular tobacco products that heat e-liquid into an aerosol for inhalation. Since their introduction to the market, electronic cigarettes have been considered a safer alternative to combustible tobacco products. However, most of today's users are adolescents and young adults naïve to tobacco products, who are drawn to e-cigarettes by appealing designs and targeted marketing, resulting in exposure to largely unknown short- and long-term health risks. While the cardiovascular effects of electronic cigarettes remain incompletely understood, there has been a growing concern surrounding their potential acute and chronic impact on cardiovascular health and disease risks. In this review, we examine the components of e-cigarettes and evaluate the cardiovascular effects of both acute and regular e-cigarette exposure, summarizing findings from existing preclinical and clinical studies to provide a comprehensive overview about the topic.

Indexed as

Cardiovascular DiseasesCardiovascular SystemE-Cigarette VaporElectronic Nicotine Delivery SystemsNicotineNicotinic AgonistsVapingAnimalsHeart Disease Risk FactorsHumansRisk AssessmentE-Cigarette VaporNicotineNicotinic AgonistsCardiotoxicityCardiovascular healthE-cigarettesTobacco products

Identifiers

PMID40825878
PMCPMC12513945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.