ArticleNature communications2025
Genetic isolation and metabolic complexity of an Antarctic subglacial microbiome.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Giant viruses of the polar regions: diversity, endemism, adaptation and ecological structuring.FEMS microbiology ecology · 2026Review
- Transcriptomic insights into unisexual flower development in Cannabis sativa: conserved MADS-box networks and divergent developmental programs.BMC plant biology · 2026Article
- Ecological differentiation at the polar frontier: metabolic strategies of endemic and cosmopolitan bacteria in Antarctic microbial mats.Frontiers in microbiology · 2026Article
- Bacteriophages in Antarctic subglacial lakes reveal novel biodiversity and biogeochemical potential.ISME communications · 2026Article
- Comparative Genomics and Phylogenomics of Novel Radiation-Resistant BacteriumMicroorganisms · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Microbes inhabiting and evolving in aquatic ecosystems beneath polar ice sheets subsist under energy-limited conditions while in relative isolation from surface gene pools and their common ancestral populations of origin. Samples obtained from beneath West Antarctic Ice Sheet (WAIS) allowed us to examine evolutionary relationships of and identify metabolic pathways in microbial genomes recovered from the Mercer Subglacial Lake (SLM) ecosystem. We obtained 1,374 single-cell amplified genomes (SAGs) from individual bacterial and archaeal cells that were isolated from samples of SLM's water column and sediments. These genomes reveal that a diversity of microorganisms including Patescibacteria exists in SLM. Comparative analyses show that most genomes correspond to new species and taxonomic groups, with phylogenomic and functional evidence supporting their genetic isolation from marine and surface biomes. Genomic data reveal diverse metabolisms in SLM that are capable of oxidizing organic and inorganic compounds via aerobic or anaerobic respiration. Distinct metabolic guild structures are observed for the subglacial populations, where trophic shifts from organotrophy to chemolithotrophy may depend on oxygen availability. Our SAG data suggest versatile metabolic capabilities in the characterized microbial assemblage, reveal key energy-generating strategies in the subglacial aquatic ecosystem, and provide a framework to assess microbial evolution beneath WAIS.
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Registered trials
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