ReviewChemistryOpen2025
Deep Eutectic Solvents in Polymeric Drug Carriers: Insights into Release Behavior and Functional Integration.
Review in ChemistryOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Eutectogels: Recent Advances, Design Strategies, and Emerging Applications in Biotechnology.Gels (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Incorporating deep eutectic solvents (DES) into polymer-based drug delivery systems (DDS) presents a novel approach to addressing persistent pharmaceutical issues, including low solubility, restricted bioavailability, and unregulated drug release. As environmentally friendly, adjustable, and biocompatible alternatives to traditional organic solvents and ionic liquids, DES possess distinctive physicochemical characteristics-such as strong hydrogen-bonding ability, low volatility, and structural flexibility-that make them effective as functional excipients. This review consolidates a contemporary understanding of the formulation and performance of polymeric matrices containing DES, highlighting their capacity to alter drug release kinetics, improve solubility, and facilitate dual-function systems like therapeutic DES (THEDES). A comprehensive overview of the various types of DES and polymeric carriers, their methods of integration, associated physicochemical effects, and drug release mechanisms is provided. Furthermore, the outline problems associated with stability, sterilization, and regulatory considerations. In addition, the most prospective future uses of DES-polymer systems is examined in stimuli-responsive systems, 3D-printed scaffolds, and advanced tailored medicine. This article supports the broader polite investigation of polymers and DES in polymeric systems in DDS as a significant step toward safer, more environmentally friendly, high-efficiency pharmaceutical technologies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.