Evidence map›Paper›PMID 40825534›Full record

ArticleBiochemistry2025

Sad from Proteobacteria is a Structurally Distinct ALDH3 Enzyme Specialized for the Oxidation of Steroidal Aldehydes.

Nicolas Rolfe, Dustin Myskiw, Matthew T Patton, Taylor J B Forrester, Matthew S Kimber, Stephen Y K Seah

Abstract read
In one paragraph

Article in Biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicolas RolfeDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Dustin MyskiwDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Matthew T PattonDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Taylor J B ForresterDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0002-5609-1453
Matthew S KimberDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0001-9454-5586
Stephen Y K SeahDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0001-5194-865X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The steroid aldehyde dehydrogenase (Sad) from Proteobacteria is a class 3 aldehyde dehydrogenase (ALDH3) that catalyzes the oxidation of C

Indexed as

Aldehyde DehydrogenaseAldehydesBacterial ProteinsProteobacteriaSteroidsCatalytic DomainCrystallography, X-RayModels, MolecularNADPOxidation-ReductionSubstrate SpecificityAldehyde DehydrogenaseAldehydesBacterial ProteinsNADPSteroids

Identifiers

PMID40825534
PMCPMC12410373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.