ArticleCirculation2025
Reformulation of the Necroptosis Pathway in Reperfused Myocardial Infarction.
Abstract readLetter
In one paragraph
Article in Circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Insights into programmed cell death from multiple imaging modalities.Journal of translational medicine · 2026Review
- Cellular and molecular signals of cardiac wound healing after myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2026Review
- Different forms of cardiomyocyte death in post-myocardial infarction ventricular remodeling: mechanisms and therapeutic strategies.Frontiers in cardiovascular medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Dongze Qin *Departments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0002-9718-8155
Radheshyam Modanwal *Departments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0002-1524-4695
Madeeha Ghazi *Departments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0003-0435-2145
J Jose Corbalan *Departments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.
Xiaotong F JiaDepartments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0002-0633-2079
Joshua L AxelrodDepartments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.
Roneldine MesidorCardiOmics Program Center for Heart and Vascular Research, Division of Cardiovascular Medicine, and Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha (R. Mesidor, R.L.G.).ORCID 0000-0002-2693-1714
Hee Jae JangDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison (H.J.J., T.J.K.).ORCID 0009-0001-3820-0011
Claudio HumeresDepartments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.
Anis HannaDepartments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0002-5212-3403
Fahimeh VarzidehDepartments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.
Michelle D TallquistCenter for Cardiovascular Research, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu (M.D.T.).ORCID 0000-0002-1383-144X
Gaetano SantulliDepartments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0001-7231-375X
Qinghang LiuDepartment of Neurobiology and Biophysics, University of Washington School of Medicine, Seattle (Q.L.).ORCID 0000-0003-0638-6509
Lorrie A KirshenbaumInstitute of Cardiovascular Sciences, St Boniface Hospital Albrechtsen Research Centre, and the Departments of Physiology and Pathophysiology and Pharmacology and Therapeutics, University of Manitoba Max Rady College of Medicine, Winnipeg, Canada (L.A.K.).ORCID 0000-0002-9617-5803
Hongmin NiDepartment of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City (H.N.).
Timothy J KampDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison (H.J.J., T.J.K.).ORCID 0000-0003-2103-7876
Rebekah L GundryCardiOmics Program Center for Heart and Vascular Research, Division of Cardiovascular Medicine, and Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha (R. Mesidor, R.L.G.).ORCID 0000-0002-9263-833X
Siddharth BalachandranCenter for Immunology, Fox Chase Cancer Center, Philadelphia, PA (S.B.).
Alexei DegterevDepartment of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA (A.D.).ORCID 0000-0002-8240-7132
John W CalvertDepartments of Surgery (Division of Cardiothoracic Surgery) and Biochemistry, Emory University School of Medicine, Atlanta, GA (J.W.C.).ORCID 0000-0001-6858-6042
Richard N KitsisDepartments of Medicine (Cardiology) (D.Q., R. Modanwal, M.G., J.J.C., X.F.J., J.L.A., C.H., A.H., F.V., G.S., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0003-1395-9694
Funding
WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8MProject 3 - Role of Proline Metabolism in Regulation of Mammalian Cardiomyocyte ProliferationP01HL160476 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jianyi Zhang · 2022 to 2026
$13.1MIntegrated Cellular and Tissue Engineering for Ischemic Heart DiseaseU01HL134764 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BURSAC, NENAD, KAMP, TIMOTHY J. · 2016 to 2022
$7.7MTargeting the orphan nuclear receptor LRH-1 with small moleculesR01DK115213 · NIDDK · EMORY UNIVERSITY · PI John Winter Calvert, Eric A Ortlund · 2017 to 2026
$4.6MHarnessing Glycoproteomics and Glycomics to Understand Cardiac Biology and DiseaseR35HL155460 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Rebekah L. Gundry · 2021 to 2026
$4.6MTargeting RIPK3 in Flu-Associated Lung InjuryR01AI144400 · NIAID · RESEARCH INST OF FOX CHASE CAN CTR · PI BALACHANDRAN, SIDDHARTH, CUNY, GREGORY D · 2019 to 2023
$3.6MRole of ZBP1 in pathogenesis of Salmonella biofilmsR01AI171568 · NIAID · RESEARCH INST OF FOX CHASE CAN CTR · PI SIDDHARTH BALACHANDRAN, Cagla Tukel · 2023 to 2026
$3.4MSmall-molecule exploitation of ZBP1-driven nuclear necroptosis for cancer immunotherapyR01CA269975 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI SIDDHARTH BALACHANDRAN, VASILY M STUDITSKY · 2023 to 2026
$3.0MMitochondrial ATP Synthase in Cardiac Biology and DiseaseR01HL157319 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI KITSIS, RICHARD N · 2022 to 2025
$2.9MModulation of Mitofusin Activity to Treat Heart DiseaseR01HL159062 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI KITSIS, RICHARD N · 2021 to 2024
$2.6MCaspase-9 as a nodal point connecting necrotic and apoptotic cell death in myocardial infarctionR01HL164772 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI KITSIS, RICHARD N · 2022 to 2025
$2.5MRegulation of CSE-Derived Hydrogen Sulfide in the HeartR01HL164806 · NHLBI · EMORY UNIVERSITY · PI John Winter Calvert, Eric A Ortlund · 2023 to 2026
$2.1MNCI NIH HHS P30 CA006927NCI NIH HHS R01 CA269975NHLBI NIH HHS P01 HL160476NHLBI NIH HHS R01 HL155035NHLBI NIH HHS R01 HL157319NHLBI NIH HHS R01 HL159062NHLBI NIH HHS R01 HL160767NHLBI NIH HHS R01 HL164772NHLBI NIH HHS R01 HL164806NHLBI NIH HHS R35 HL155460NHLBI NIH HHS U01 HL134764NIAID NIH HHS R01 AI144400NIAID NIH HHS R01 AI171568NIDDK NIH HHS R01 DK115213
Abstract
PubMed holds no abstract for this paper.
Indexed as
cell deathmyocardial infarctionnecroptosis
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