ArticlePloS one2025
Effect of psychological interventions on outcomes for caregivers of hematopoietic stem cell transplant patients: Protocol for a systematic review and planned meta-analysis.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Nurse-Led Interventions and Outcomes in Adult Hematopoietic Stem Cell Transplant Recipients: A Scoping Review.Nursing reports (Pavia, Italy) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Caregivers of Hematopoietic Stem Cell Transplant (HSCT) recipients bear significant responsibilities involving commitment to be available 24/7, up to at least 100 days post-transplant or longer, and to provide emotional and physical support to the recipient. This extended caregiving, along with managing all other household responsibilities, can result in an increased caregiver burden, which is associated with reduced quality of life (QoL) and compromised psychological, and physical well-being. In recent years, there has been increased attention to interventions addressing the mental health outcomes of caregivers of HSCT patients. However, there remains a limited understanding of the feasibility and effectiveness of existing interventions targeted to this population. This review aims to systematically evaluate existing psychological interventions for caregivers of HSCT patients and report on: 1) the feasibility and acceptability of these interventions, and 2) the efficacy of these interventions on caregivers' psychological outcomes. A systematic literature search for studies evaluating psychological interventions targeted to caregivers of HSCT patients was conducted in English through the following databases: Ovid MEDLINE (Wolters Kluwer), Embase (Elsevier), CINAHL Complete (EBSCO), APA PsycArticles (EBSCO), APA PsycInfo (EBSCO). Two reviewers will independently identify the studies, extract relevant data, and conduct quality and risk of bias assessments. Discrepancies in coding will be discussed between the two reviewers, and a third reviewer will resolve pending disagreements. Within the systematic review, all eligible studies will be summarized descriptively. If data allows, we will further utilize meta-analysis to quantitatively evaluate the efficacy of these psychological interventions tested in RCTs. The association between intervention type, modality, duration, and efficacy will be assessed via subgroup analysis. Ethics approval is not required as this study will only include secondary data from already published studies. The outcomes will be shared through scientific conferences and peer-reviewed publications. This protocol is registered in PROSPERO: CRD42024489695.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.